A pilot replication of QUIT, a randomized controlled trial of a brief intervention for reducing risky drug use, among Latino primary care patients.

Drug Alcohol Depend

Division of Epidemiology, Department of Sport and Health Sciences, Technical University of Munich, Munich, Germany; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.

Published: October 2017

AI Article Synopsis

  • The QUIT intervention effectively reduced risky drug use among Latino patients in a primary care setting, demonstrating its applicability outside of the original study locations.
  • Participants in the intervention group received brief clinician advice, a supportive video, educational materials, and follow-up coaching, leading to a significant reduction in high-scoring drug use days.
  • Results indicated a 40% reduction in drug use among intervention patients, with them also showing a lower likelihood of testing positive for drug use compared to the control group.

Article Abstract

Background: QUIT is the only primary care-based brief intervention that has previously shown efficacy for reducing risky drug use in the United States (Gelberg et al., 2015). This pilot study replicated the QUIT protocol in one of the five original QUIT clinics primarily serving Latinos.

Design: Single-blind, two-arm, randomized controlled trial of patients enrolled from March-October 2013 with 3-month follow-up.

Setting: Primary care waiting room of a federally qualified health center (FQHC) in East Los Angeles.

Participants: Adult patients with risky drug use (4-26 on the computerized WHO ASSIST): 65 patients (32 intervention, 33 control); 51 (78%) completed follow-up; mean age 30.8 years; 59% male; 94% Latino.

Interventions And Measures: Intervention patients received: 1) brief (typically 3-4 minutes) clinician advice to quit/reduce their risky drug use, 2) video doctor message reinforcing the clinician's advice, 3) health education booklet, and 4) up to two 20-30 minute follow-up telephone drug use reduction coaching sessions. Control patients received usual care and cancer screening information. Primary outcome was reduction in number of days of drug use in past 30days of the highest scoring drug (HSD) on the baseline ASSIST, from baseline to 3-month follow-up.

Results: Controls reported unchanged HSD use between baseline and 3-month follow-up whereas Intervention patients reported reducing their use by 40% (p<0.001). In an intent-to-treat linear regression analysis, intervention patients reduced past month HSD use by 4.5 more days than controls (p<0.042, 95% CI: 0.2, 8.7). Similar significant results were found using a complete sample regression analysis: 5.2 days (p<0.03, 95% CI: 0.5, 9.9). Additionally, on logistic regression analysis of test results from 47 urine samples at follow-up, intervention patients were less likely than controls to test HSD positive (p<0.05; OR: 0.10, 95% CI: 0.01, 0.99).

Conclusions: Findings support the efficacy of the QUIT brief intervention for reducing risky drug use.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796764PMC
http://dx.doi.org/10.1016/j.drugalcdep.2017.04.022DOI Listing

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