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A morphometric analysis of the cranial base in trigonocephaly.
J Craniomaxillofac Surg
January 2025
Department of Clinical Anatomy, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa. Electronic address:
Trigonocephaly occurs when the metopic suture fuses prematurely. Few studies have documented the morphometry of the entire anterior cranium in trigonocephaly and not on the morphometric changes to the cranial fossae alone. Thus, this study aimed to determine and compare the dimensions of the anterior cranial fossa (ACF) in trigonocephaly and control groups.
View Article and Find Full Text PDFClinical presentation of hemifacial microsomia in a South African population.
J Plast Surg Hand Surg
January 2025
Discipline of Clinical Anatomy, School of Laboratory Medicine and Medical Sciences, Westville Campus University of KwaZulu-Natal, Durban, South
Background: Hemifacial microsomia (HFM) presentation includes gross distorted ramus, malposition temporomandibular joint, small glenoid fossa, distorted condyle and notch, malformed orbit, cupping ear or absent external ear, and facial nerve palsy. HFM is the second most prevalent congenital deformity of the face, with little literature from the South African population. This retrospective study elucidated the demographic characteristics and clinical presentations of HFM patients in a select South African population and compared it to the literature.
View Article and Find Full Text PDFGlobal consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR).
J Nutr Health Aging
January 2025
Faculty of Medicine and Health, School of Health Sciences and Sydney Medical School, University of Sydney, New South Wales, Australia, and Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Roslindale, MA, United States.
Article Synopsis
- Aging leads to physiological changes and increased disease vulnerability, culminating in higher mortality rates as individuals get older.
- Regular physical activity (PA) and exercise can counteract aging effects, improve health span, and reduce the risk of chronic diseases such as heart disease and cancer.
- Personalized exercise plans, including various forms of training like aerobic and resistance exercises, are essential for maintaining health and functionality in older adults, particularly those with age-related issues.
Neuro-toxicities of chemo- and immune-therapies in haematologic malignancies: from mechanism to management.
Blood Rev
January 2025
Centre for Haematology, Imperial College of Science, Technology and Medicine, London, UK; Department of Hematologic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, China.
Chemo- and immune therapies administered to treat haematologic malignancies frequently cause neurologic injury. The adverse events range from mild cognitive impairment and headaches to severe conditions such as seizures, stroke and encephalitis. We performed a comprehensive literature review and report the types, mechanisms, management and prevention of neuro-toxicity resulting from these therapies in subjects who develop these toxic effects.
View Article and Find Full Text PDFRedefining Diagnostic Cut-Offs for the Indirect Water Deprivation Test.
Clin Endocrinol (Oxf)
February 2025
Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism Digestion and Reproduction, Imperial College London, London, UK.
Objective: An incorrect diagnosis of arginine vasopressin deficiency and resistance (AVP-D and AVP-R) results in the potentially dangerous use of desmopressin in healthy individuals. The water deprivation test is a central diagnostic test in patients with polydipsia polyuria syndrome (PPS). This study aims to determine the effectiveness of the current interpretation of reference ranges.
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