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Working memory (WM) is an evolving concept. Our understanding of the neural functions that support WM develops iteratively alongside the approaches used to study it, and both can be profoundly shaped by available tools and prevailing theoretical paradigms. Here, the organizers of the 2024 Working Memory Symposium-inspired by this year's meeting-highlight current trends and looming questions in WM research.
View Article and Find Full Text PDFEvaluation of piperacillin-tazobactam disks using contemporary Enterobacterales isolates suggests the need for disk potency optimization.
J Clin Microbiol
January 2025
Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Unlabelled: Piperacillin-tazobactam (TZP) is a commonly used broad-spectrum agent. OXA-1 β-lactamases drive global Enterobacterales TZP resistance and raise MICs to the clinical breakpoints (8/4-16/4 µg/mL), making susceptibility testing challenging. Two TZP disks are used globally.
View Article and Find Full Text PDFRefining bone marrow ablation and reconstitution in mice.
Immunol Cell Biol
January 2025
The Babraham Institute, Babraham Hall, Cambridge, UK.
This report presents findings from a group of UK-based researchers with expertise in the use of animal models for bone marrow ablation and reconstitution. The primary aim is to facilitate the implementation of the Three Rs (Replacement, Reduction and Refinement), with an emphasis on refinement. Bone marrow ablation and reconstitution procedures are performed for a number of different purposes and conducted predominantly in mice.
View Article and Find Full Text PDFComparison of fractionation methods to assess Ni impact on anaerobic digestion: Filtration versus DGT.
J Hazard Mater
January 2025
E2Lim - Eau et Environnement Limoges UR 24133, University of Limoges, Limoges, France.
Excess of trace elements (TE) significantly alters the performances of anaerobic digestors (AD). Due to interactions with organic matter in particular, only a small fraction of TE can effectively interact with the biomass. However, assessing the bioavailable fraction of TE remains an issue.
View Article and Find Full Text PDFHistorical and Contemporary Perspectives: Metaphorical Significance of Tooth Extraction in Lithographs and Postcards in the 19th and 20th Centuries in Their Specific Socio-Historical Context.
J Hist Dent
January 2025
Founding member of "Arbeitskreis für die Geschichte der Zahnheilkunde" - Chapter of Deutsche Gesellschaft für Zahn-Mund und Kieferheilkunde - DGZMK (German Society of the History of Dentistry).
In historical illustrations and caricatures, the extraction of a tooth served as a powerful metaphor and threatening gesture that extended far beyond the medical context. This article examines the symbolic significance of this dental procedure and the extracted tooth as an expression of loss, disempowerment, and territorial dispossession. The comparison covers a wide range of visual representations from the French Revolution (1789-1799), the French July Revolution (1830), the Crimean War (1853-1856), the Austro-Prussian War (1866), the Franco-Prussian War (1870/71), to the First (1914-1918) and Second (1939-1945) World Wars and places them in their respective historical contexts.
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