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[Application of modern methods for activation of brain functions in obese patients (literature review)].
Vopr Kurortol Fizioter Lech Fiz Kult
December 2024
Saratov State Medical University named after V. I. Razumovsky, Saratov, Russia.
Unlabelled: The problem of rational activation of functions of the central nervous system of a human remains highly relevant.
Objective: To analyze scientific data on the use of transcranial exposure method in obesity.
Results: The literature review presents current data on the effectiveness of non-invasive hardware brain neurostimulation in obese patients.
A Multisite, 6-Month, Open-Label Study of Maintenance Transcranial Magnetic Stimulation for Adolescents with Treatment-Resistant Depression.
J Child Adolesc Psychopharmacol
December 2024
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA.
Transcranial magnetic stimulation (TMS) is a promising intervention for adolescents with treatment-resistant depression (TRD). However, the durability of TMS-related improvement in adolescents is unclear. This 6-month study followed adolescents with TRD who had responded to TMS and provided TMS retreatment for adolescents with a partial relapse.
View Article and Find Full Text PDFGut-brain axis and neuroplasticity in health and disease: a systematic review.
Radiol Med
December 2024
Medical Physics Department, Bambino Gesù Children's Hospital, 00165, Rome, Italy.
The gut microbiota emerged as a potential modulator of brain connectivity in health and disease. This systematic review details current evidence on the gut-brain axis and its influence on brain connectivity. The initial set of studies included 532 papers, updated to January 2024.
View Article and Find Full Text PDFDifferential effects of stimulation waveform and intensity on the neural structures activated by lumbar transcutaneous spinal cord stimulation.
J Neurophysiol
December 2024
Spinal Cord Injury Research Centre, Neuroscience Research Australia, Randwick, 2031 NSW, Australia.
Introduction: Lumbar transcutaneous spinal cord stimulation (TSS) evokes synchronized muscle responses, termed spinally evoked motor response (sEMR). Whether the structures TSS activates to evoke sEMRs differ when TSS intensity and waveform are varied is unknown.
Methods: In 15 participants (9F:6M), sEMRs were evoked by TSS over L1-L3 (at sEMR threshold and suprathreshold intensities) using conventional (one 400-µs biphasic pulse) or high-frequency burst (ten 40-µs biphasic pulses at 10 kHz) stimulus waveforms in vastus medialis (VM), tibialis anterior (TA) and medial gastrocnemius (MG) muscles.
Open label pilot of personalized, neuroimaging-guided theta burst stimulation in early-stage Alzheimer's disease.
Front Neurosci
December 2024
Memory and Brain Wellness Center, University of Washington, Seattle, WA, United States.
Background: Alzheimer's disease (AD) is characterized by cerebral amyloid plaques and neurofibrillary tangles and disruption of large-scale brain networks (LSBNs). Transcranial magnetic stimulation (TMS) has emerged as a potential non-invasive AD treatment that may serve as an adjunct therapy with FDA approved medications.
Methods: We conducted a 10-subject open label, single site study evaluating the effect of functional connectivity-resting state functional MRI guided-approach to TMS targeting with dysfunctional LSBNs in subjects with biomarker-confirmed early-stage AD (https://clinicaltrials.
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