Lower gastrointestinal bleeding (LGIB) is a common problem that can be treated via a number of endoscopic, radiological and surgical approaches. Although traditionally managed by the colorectal surgeons, surgery should be considered a last resort given the variety of endoscopic and radiological approaches available. This article provides an overview on the common causes of acute LGIB and the various techniques at our disposal to control it.
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http://dx.doi.org/10.1136/flgastro-2015-100606 | DOI Listing |
Simul Healthc
December 2024
From the Department of Human Structure and Repair, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium (L.D.M., I.V.H., L.D., W.W.); Department of Thoracic and Vascular Surgery, Ghent University Hospital, Ghent, Belgium (I.V.H., L.D.); Department of Basic and Applied Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium (P.V.d.V.); Department of Emergency Medicine, Ghent University Hospital, Ghent, Belgium (P.V.d.V.); Department of Gastrointestinal Surgery, Ghent University Hospital, Ghent, Belgium (H.V., W.W.); Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (L.K.); and Copenhagen Academy for Medical Education and Simulation (CAMES), Copenhagen, Denmark (L.K.).
Introduction: Chest tube insertions (CTIs) have a high complication rate, prompting the training of technical skills in simulated settings. However, assessment tools require validity evidence prior to their implementation. This study aimed to collect validity evidence for assessment of technical skills in CTI on Thiel-embalmed human bodies.
View Article and Find Full Text PDFPLoS Pathog
January 2025
Liver Diseases Branch, NIDDK, NIH, Bethesda, Maryland, United States of America.
HBV genotype A has two major subtypes, A1 (commonly in Africa) and A2 (commonly in Europe) with only 4% nucleotide differences. Individuals infected with these two subtypes appear to have different clinical manifestations and virologic features. Whether such a difference results from the virus or host has not been established.
View Article and Find Full Text PDFPLoS One
January 2025
Fujian Key Laboratory of Lung Stem Cells, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.
Introduction: Pulmonary fibrosis (PF) is a chronic and irreversible interstitial lung disease characterized by a lack of effective therapies. Mesenchymal stem cells (MSCs) have garnered significant interest in the realm of lung regeneration due to their abundant availability, ease of isolation, and capacity for expansion. The objective of our study was to investigate the potential therapeutic role of umbilical cord-derived MSCs (UC-MSCs) in the management of PF, with a focus on the alterations in the gut microbiota and its metabolites during the use of UC-MSCs for the treatment of pulmonary fibrosis, as well as the possible mechanisms involved.
View Article and Find Full Text PDFGastric Cancer
January 2025
Department of Gastrointestinal Surgery, Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao, China.
Background: Laparoscopic gastrectomy lacks hand-direct tactile sense and has a limited surgical field compared to laparotomy. Apart from textbook classification, there are anatomical variations in the gastric arteries. Laparoscopic gastrectomy presents technical difficulties and necessitates a more comprehensive comprehension of regional anatomy than open surgical procedures.
View Article and Find Full Text PDFBackground: Gut microbiome features have been linked with many diseases including Alzheimer's disease (AD). Evidence suggests that the gut microbiota may impact cognition of AD patients. We explored the association of gut microbiota and three PACC3 cognitive scores in individuals at risk for AD.
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