Background: Upper oesophageal webs or rings have rarely been reported in association with heterotopic gastric mucosa (HGM).
Objective: To describe the finding of oesophageal webs in association with HGM.
Design: Small case series.
Setting: Patients presenting with dysphagia to an open access hospital dysphagia clinic.
Patients: Six cases were found.
Interventions: Symptomatic improvement is demonstrated with oesophageal dilatation in symptomatic patients.
Main Outcome Measurements: Symptomatic improvement.
Results: The six cases which are described here demonstrate that a web or ring exactly matches the distribution of the heterotopic mucosa, can occur at both proximal and distal squamo-columnar junctions and the inlet patches may be multiple with multiple rings. A radiological double web sign is described.
Limitations: A rare condition with a small number of patients.
Conclusions: Effective treatment can be by oesophageal dilatation and acid suppression. The cause of web formation is thought to be due to heterotopic acid production and is analogous to the Schatzki ring.
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http://dx.doi.org/10.1136/fg.2010.002311 | DOI Listing |
Anal Cell Pathol (Amst)
January 2025
Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, People's Republic of China, Research Unit of Key Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, No. 168 Changhai Road, Shanghai 200433, China.
Trauma and burns are leading causes of death and significant global health concerns. RNA-binding proteins (RBPs) play a crucial role in post-transcriptional gene regulation, influencing various biological processes of cellular RNAs. This study aims to review the emerging trends and key areas of research on RBPs in the context of trauma and burns.
View Article and Find Full Text PDFJ Transl Med
January 2025
Department of Clinical Laboratory, The First Hospital of Jilin University, Changchun, 130000, China.
Background: Recent studies suggest a connection between immunoglobulin light chains (IgLCs) and coronary heart disease (CHD). However, current diagnostic methods using peripheral blood IgLCs levels or subtype ratios show limited accuracy for CHD, lacking comprehensive assessment and posing challenges in early detection and precise disease severity evaluation. We aim to develop and validate a Coronary Health Index (CHI) incorporating total IgLCs levels and their distribution.
View Article and Find Full Text PDFBMC Bioinformatics
January 2025
International Institute "Solution Chemistry of Advanced Materials and Technologies", ITMO University, Saint-Petersburg, Russian Federation, 191002.
Background: Deoxyribozymes or DNAzymes represent artificial short DNA sequences bearing many catalytic properties. In particular, DNAzymes able to cleave RNA sequences have a huge potential in gene therapy and sequence-specific analytic detection of disease markers. This activity is provided by catalytic cores able to perform site-specific hydrolysis of the phosphodiester bond of an RNA substrate.
View Article and Find Full Text PDFImmunopharmacol Immunotoxicol
January 2025
Department of Oral & Maxillofacial Surgery, College of Stomatology, Guangxi Medical University, Nanning, Guangxi, China.
Objective: Osteoimmunology is an emerging field that explores the interplay between bone and the immune system. The immune system plays a critical role in the pathogenesis of diabetes and significantly affects bone homeostasis. Artesunate, a first-line treatment for malaria, is known for its low toxicity and multifunctional properties.
View Article and Find Full Text PDFPhotodiagnosis Photodyn Ther
January 2025
Department of Radiation Oncology, The Third Affiliated Hospital of Shandong First Medical University (Affiliated Hospital of Shandong Academy of Medical Sciences), Jinan, Shandong, China. Electronic address:
Background: Cholangiocarcinoma is a rare but highly fatal malignancy; numerous studies have demonstrated promising outcomes and survival rates associated with adjuvant photodynamic therapy (PDT) in the palliative treatment of cholangiocarcinoma.
Objective: To systematically evaluate the existing meta-analyses on PDT for cholangiocarcinoma, assessing evidence quality and strength while performing updated meta-analyses to refine survival outcomes.
Methods: PubMed, EMBASE, Cochrane Library, and Web of Science were systematically searched up to September 18, 2024, to identify meta-analyses and clinical studies on PDT in patients with cholangiocarcinoma.
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