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The creation and study of brain organoids may hold significant promise for understanding brain functions, disorders, and diseases. This research may also raise novel considerations and ethical concerns, but it has significant public and professional support when thoughtfully undertaken. Current legislative and judicial restrictions on abortion and pronouncements about fetal personhood could, however, have a surprisingly broad and unintended reach, even conceivably restricting the development and use of brain organoids and other biomedical and bioengineered research tools.
View Article and Find Full Text PDFThe superficial radial artery-a cautionary tale of two pedicles.
Int J Oral Maxillofac Surg
March 2025
Oral and Maxillofacial Surgery Department, Morriston Hospital NHS, Swansea, Wales, UK. Electronic address:
The radial forearm free flap is a common reconstructive option following ablative head and neck surgery. Although uncommon, anatomical variants such as radial artery anomalies pose risks to flap harvest and viability. A rare case of a common radial artery that branched distally into a superficial radial artery and a deep radial artery is reported here.
View Article and Find Full Text PDFTo Catch a Catfish: A Cautionary Tale of Internet Unprofessionalism.
J Grad Med Educ
February 2025
is Program Director, Pediatric Residency Program, and Assistant Dean of Medical Education, Baylor College of Medicine, CHRISTUS Children's, San Antonio, Texas, USA.
Septal Branch Occlusion Leading to Complete Heart Block Post-Percutaneous Intervention: A Cautionary Tale in Left Bundle Branch Block Patients.
Catheter Cardiovasc Interv
February 2025
Cardiology Department, Holy Name Medical Center, Teaneck, New Jersey, USA.
A 66-year-old man with a baseline electrocardiogram (ECG) showing left bundle branch block developed persistent complete atrioventricular block following stent placement in the proximal left anterior descending artery (LAD), necessitating permanent pacemaker implantation. The complication is believed to have resulted from occlusion of the second septal branch, which likely supplied the right bundle of the His system. During elective interventions targeting the LAD in patients with pre-existing conduction abnormalities, it is crucial to maintain adequate blood flow to the septal perforators.
View Article and Find Full Text PDFThree Cell Wall Degrading Enzymes and Sorghum Contribute to Virulence and Resistance in the Bacterial Leaf Streak Pathosystem.
Mol Plant Microbe Interact
March 2025
Donald Danforth Plant Science Center, St. Louis, MO 63132, U.S.A.
With an increasing demand for renewable fuels, bioenergy crops are being developed with high sugar content and altered cell walls to improve processing efficiency. These traits may have unintended consequences for plant disease resistance. pv.
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