Sucrose non-fermenting-1 (SNF1)-related protein kinase 2s (SnRK2s) that were reported to be involved in the transduction of abscisic acid (ABA) signaling, play important roles in response to biotic and abiotic stresses in plants. Compared to the systemic investigation of in and , little is known regarding in soybean, which is one of the most important oil and protein crops. In the present study, we performed genome-wide identification and characterization of in soybean. In summary, 22 were identified and clustered into four groups. Phylogenetic analysis indicated the expansion of gene family during the evolution of soybean. Various -acting elements such as ABA Response Elements (ABREs) were identified and analyzed in the promoter regions of . The results of RNA sequencing (RNA-Seq) data for different soybean tissues showed that exhibited spatio-temporally specific expression patterns during soybean growth and development. Certain could respond to the treatments including salinity, ABA and strigolactones. Our results provide a foundation for the further elucidation of the function of genes in soybean.
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http://dx.doi.org/10.3390/ijms18091834 | DOI Listing |
Aging Clin Exp Res
January 2025
Department of Joint Surgery, HongHui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Objective: Osteoarthritis (OA) represents a condition under the influence of central nervous system (CNS) regulatory mechanisms. This investigation aims to examine the causal association between viral infections of the central nervous system (VICNS) and inflammatory diseases of the central nervous system (IDCNS) and knee osteoarthritis (KOA) at the genetic level.
Methods: In this investigation, VICNS and IDCNS were considered as primary exposure variables, while KOA served as the primary outcome.
J Headache Pain
January 2025
Clinical Systems Biology Laboratories, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Background: Migraine is a complex neurological disorder characterized by recurrent episodes of severe headaches. Although genetic factors have been implicated, the precise molecular mechanisms, particularly gene expression patterns in migraine-associated brain regions, remain unclear. This study applies machine learning techniques to explore region-specific gene expression profiles and identify critical gene programs and transcription factors linked to migraine pathogenesis.
View Article and Find Full Text PDFJ Adv Res
January 2025
Department of Oncology, The First Affiliated Hospital, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences Xi'an Jiaotong University Xi'an Shanxi China. Electronic address:
Introduction: Ferroptosis is an iron-dependent form of cell death triggered by the excessive accumulation of lipid peroxides. Understanding the regulatory mechanisms of ferroptosis and developing strategies to target this process hold significant clinical applications in tumor therapy.
Objective: Our study aims to search for novel candidate genes involved in the regulation of ferroptosis and to investigate their mechanism of action in ferroptosis and tumor therapy.
Front Immunol
January 2025
Department of Stomatology, The People's Hospital of Deyang City, Deyang, Sichuan, China.
Background: Periodontal disease is a widespread inflammatory condition that compromises the supporting structures of the teeth, potentially resulting in tooth loss if left untreated. Despite advancements in therapeutic interventions and an enhanced understanding of its pathophysiology, emerging techniques such as single-cell RNA sequencing (scRNA-seq) and Mendelian randomization (MR) present new opportunities for precision medicine in the management of periodontal disease.
Methods: Data derived from the GSE152042 dataset underwent rigorous quality control, normalization, and dimensionality reduction using Seurat and the MonacoImmuneData framework.
Mol Breed
February 2025
Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, QLD 4072 Australia.
Unlabelled: Spot blotch (SB), a prevalent foliar disease of barley, is caused by the hemibiotrophic fungal pathogen . Predominately occurring in humid growing regions worldwide, SB can result in yield losses of up to 30%. Genetic resistance remains the most effective strategy for disease management; however, most Australian barley cultivars exhibit susceptibility despite the previous identification of major resistance loci.
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