A new double functionalization reaction of alkenes through AgNO-mediated phosphinoyl radical addition followed by Cu(II)-catalyzed amination is introduced. This one-pot, three-component reaction is performed under mild conditions to afford α,β-aminophosphinoylation products.
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Department of Chemistry, University of Massachusetts Boston, Massachusetts 02125, United States.
A new double functionalization reaction of alkenes through AgNO-mediated phosphinoyl radical addition followed by Cu(II)-catalyzed amination is introduced. This one-pot, three-component reaction is performed under mild conditions to afford α,β-aminophosphinoylation products.
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