The relationship between exposure to hepatitis B virus and increased atherosclerosis-associated morbidity - a meta-analysis.

Kardiol Pol

Department of Neurology, Guangdong Key Laboratory for Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department, National Key Discipline, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Published: November 2018

Background And Aim: The relationship between exposure to hepatitis B virus (HBV) and atherosclerosis-associated disease morbidity has not been clearly elucidated. We performed a meta-analysis to explore whether exposure to HBV is a risk factor for atherosclerosis-associated diseases.

Methods: We searched the PubMed, Web of Science, Cochrane Library, Embase, and Scopus databases for related studies. We then chose the eligible studies for meta-analysis and assessed quality assessment and risk of bias.

Results: The meta-analysis of the included studies showed that exposure to HBV tends to increase atherosclerosis-associated disease morbidity, but this increase was not statistically significant.

Conclusions: Hepatitis B virus may not be a risk factor for atherosclerosis-associated diseases, but further studies that employ more sensitive clinical parameters are needed to verify this result.

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http://dx.doi.org/10.5603/KP.a2017.0165DOI Listing

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