Non-convulsive status epilepticus (NCSE) is a complex and diverse condition which is often an under-recognised entity in the intensive care unit. When NCSE is identified the optimal treatment strategy is not always clear. Areas covered: This review is based on a literature review of the key literature in the field over the last 5-10 years. The articles were selected based on their importance to the field by the authors. Expert commentary: This review discusses the complex situations when a neurological consultation may occur in a critical care setting and provides an update on the latest evidence regarding the recognition of NCSE and the decision making around determining the aggressiveness of treatment. It also considers the ictal-interictal continuum of conditions which may be met with, particularly in the era of continuous EEG, and provides an approach for dealing with these. Suggestions for how the field will develop are discussed.
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http://dx.doi.org/10.1080/14737175.2017.1369880 | DOI Listing |
Acta Neurol Belg
December 2024
Department of Neurology, University Hospital of Liège, Avenue de l'Hôpital 1, 4000, Liège, Belgium.
Acta Neurol Belg
December 2024
Lamezia Terme Hospital, Catanzaro, Italy.
Rinsho Shinkeigaku
December 2024
Department of Neurology, Nakamura Memorial Hospital.
The patient was a 69-year-old right-handed woman. She had sensory aphasia, and the brain MRI revealed a subacute phase hemorrhage in the left subcortical temporal lobe. We speculated that the patient had post-ictal aphasia due to symptomatic epileptic seizures associated with cerebral hemorrhage.
View Article and Find Full Text PDFNeurol Clin
February 2025
Department of Neurology, University of Lausanne, Lausanne, Switzerland. Electronic address:
In patients with status epilepticus (SE), the underlying biologic background represents the main prognostic variable. A swift application of a treatment protocol is recommended, including adequate doses of a benzodiazepine followed by an intravenous anti-seizure medicine. If refractory SE arises, general anesthetics should be used in generalized convulsive and non-convulsive SE in coma, while further non-sedating anti-seizure medications attempts are warranted in patients with focal forms.
View Article and Find Full Text PDFClin Neurophysiol
December 2024
Department of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, MD 21224, USA; Epilepsy Center, Department of Neurology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA. Electronic address:
Objective: CT hyper-perfusion has been reported in non-convulsive status epilepticus (NCSE), while its occurrence and relevance after single seizures or with rhythmic and periodic patterns (RPPs) that lie along the ictal-interictal continuum (IIC), remain unclear. The goal of the study is to assess the role of CT perfusion (CTP) in diagnosing patients with clinical seizures, subclinical seizures, or RPPs that lie along the IIC, to help in the clinical assessment of these entities.
Methods: We retrospectively reviewed inpatients who underwent a CTP and an EEG within 6 h of each other.
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