A sensitive turn-on luminescent sensor for HO based on the silver nanoparticle (AgNP)-mediated quenching of an luminescent Ir(III) complex (Ir-1) has been designed. In the absence of HO, the luminescence intensity of Ir-1 can be quenched by AgNPs via non-radiative energy transfer. However, HO can oxidize AgNPs to soluble Ag cations, which restores the luminescence of Ir-1. The sensing platform displayed a sensitive response to HO in the range of 0-17 μM, with a detection limit of 0.3 μM. Importantly, the probe was successfully applied to monitor intracellular HO in living cells, and it also showed high selectivity for HO over other interfering substances.
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| http://dx.doi.org/10.1038/s41598-017-09478-6 | DOI Listing |
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