AI Article Synopsis
- Croton cajucara Benth. is a medicinal plant from the Brazilian Amazon, known as sacaca, and is commonly consumed in teas or infusions.
- A detailed phytochemical analysis was performed on its leaf decoction using liquid chromatography-mass spectrometry, identifying several compounds previously unreported in this plant, including glycosides, flavonoids, tannins, and cinnamic acid derivatives.
- The identified compounds were tested for anti-inflammatory activity in a mouse model, showing that all fractions had strong anti-inflammatory properties.
Article Abstract
Croton cajucara Benth. is a medicinal plant popularly used in the Brazilian Amazonia, where it is known as sacaca, being consumed as tea, decoction or infusion of the leaves and stem bark. From a decoction of the leaves, a comprehensive phytochemical analysis was developed by liquid chromatography-mass spectrometry. Many compounds were identified for the first time in C. cajucara, such as O-glycosides of kaempferol and quercetin, flavonoid-C-glycosides, tannins and cinnamic acid derivatives. These compounds were fractionated by polarity and assayed for their anti-inflammatory activity, using a model of mice edema, induced by an intraplantar injection of carrageenan. All fractions exhibited anti-inflammatory properties.
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| http://dx.doi.org/10.1016/j.jpba.2017.07.032 | DOI Listing |
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