An efficient CuCl/EtN-catalyzed tandem reaction for the synthesis of indanone-fused pyrrolidine was developed. In this process, two rings and four bonds are generated in one pot with high atom-economy and step-efficiency. The addition of EtN was found as the key factor for the success of the tandem reaction.
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http://dx.doi.org/10.1021/acs.orglett.7b02121 | DOI Listing |
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