Introduction: Optic nerve head drusen are congenital calcium deposits located in the prelaminar section of the optic nerve head. Their association with visual field defects has been classically described, but the diagnosis of glaucoma is not easy in these cases of altered optic nerve head anatomy.
Case Study: We describe the case of a 67-year-old man with optic nerve head drusen complicated by glaucoma, which was confirmed by visual field and OCT examination of the peripapillary retinal nerve fiber layer (RNFL), but the measurement of the minimum distance between the Bruch membrane opening and the internal limiting membrane (minimum rim width, BMO-MRW) by OCT was normal.
Discussion: OCT of the BMO-MRW is a new diagnostic tool for glaucoma. Superficial optic nerve head drusen, which are found between the internal limiting membrane and the Bruch's membrane opening, overestimate the value of this parameter.
Conclusion: BMO-MRW measurement is not adapted to cases of optic nerve head drusen and can cause false-negative results for this parameter, and the diagnosis of glaucoma in this case should be based on other parameters such as the presence of a fascicular defect in the retinal nerve fibers, RNFL or macular ganglion cell complex thinning, as well as visual field data.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jfo.2016.07.027 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Smartphone-Detected Physiologic Photoleukocoria With Visible Optic Nerve Details.
Pediatrics
March 2025
Department of Ophthalmology, Virginia Commonwealth University, Richmond, Virginia.
A 13-month-old girl and a 3-year-old boy were referred to pediatric ophthalmology for leukocoria noticed on a smartphone photograph obtained by the family. Ophthalmologic examination revealed visual acuity appropriate for age and normal dilated fundus exams in both children without signs of retinoblastoma or other ocular abnormalities. Further review of the home photographs revealed optic nerve details in the leukocoric eyes.
View Article and Find Full Text PDFFractal Dimension Analysis of Peripapillary Microvasculature in Primary Congenital Glaucoma.
J Glaucoma
March 2025
Department of Ophthalmology, Harvey and Bernice Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR.
Precis: In this prospective multicenter study, eyes with primary congenital glaucoma exhibited lower retinal vascular parameters compared to healthy controls, as assessed by optical coherence tomography angiography fractal dimension analysis.
Purpose: To study the retino-choroidal peripapillary microvascular pattern in primary congenital glaucoma (PCG) using fractal dimension (FD) analysis and compare it to healthy controls.
Methods: This was a prospective multicenter comparative study.
Injective hydrogel encapsulating dental pulp stem cells for the treatment of traumatic optic nerve injury.
Front Bioeng Biotechnol
February 2025
Center of Regenerative Medicine, Renmin Hospital of Wuhan University, Wuhan, China.
Objectives: The study aimed to evaluate the effect of GeLMA/bFGF hydrogel loaded with dental pulp stem cells (DPSCs) on the repair and regeneration of traumatic optic nerve injury.
Materials And Methods: GeLMA/bFGF hydrogel was photo-cross-linked by LED light. The physical-chemical properties and cytocompatibility of GeLMA/bFGF hydrogel after being squeezed (GeLMA/bFGF-SQ) were evaluated by SEM and degradation analyses, as well as live/dead and CCK-8 assays, respectively.
Gamma Knife Radiosurgery for optic nerve sheath meningioma: comparison of efficacy and costs with radiotherapy under Korean health insurance system.
J Neurooncol
March 2025
Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Korea.
Purpose: To survey the real-world effectiveness and cost of optic nerve sheath meningioma (ONSM) treating with Gamma Knife Radiosurgery (GKRS), and compare with the external beam radiation therapy (EBRT).
Methods: Retrospective, comparative study that included patients with primary ONSM treated with either GKRS or EBRT in Samsung Medical Center, Korea. The treatment response, and treatment costs were compared between GKRS and EBRT groups.
Unusual fundus lesion in mosaic neurofibromatosis type 2.
Ophthalmic Genet
March 2025
W. K. Kellogg Eye Center, Department of Ophthalmology, University of Michigan, Ann Arbor, Michigan, USA.
Background: Neurofibromatosis is a neurocutaneous syndrome that predisposes individuals to a variety of tumors. In type 2, these typically do not present until early adulthood. We present a case of an unusual fundus lesion in neurofibromatosis type 2 (NF2) in a young child.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!