Testicular melanotic neuroectodermal tumor of infancy (MNTI) is extremely rare, with 2 cases reported in the literature. Its rarity and rapid and infiltrative growth pattern pose a diagnostic challenge. A previously healthy 3-month-old male, presented with a history of worsening left hemiscrotal swelling for 1 week. An outside ultrasound was suggestive of testicular torsion. Left orchiectomy demonstrated a mass occupying almost entire testicle with a variegated cut surface, with areas of pigmentation, necrosis, and hemorrhage. Histological examination confirmed MNTI of the testis and epididymis. MNTI should be included in differential diagnosis in infants presenting with fast-growing scrotal swelling.
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[Melanotic neuroectodermal tumor of infancy: a clinicopathological analysis of two cases].
Zhonghua Bing Li Xue Za Zhi
January 2025
Department of Pathology, Children's Hospital of Fudan University Anhui Hospital (Anhui Provincial Children's Hospital), Hefei230051, China.
Clinicopathological study of a rare neuroectodermal neoplasm of the cranium.
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Department of Neuropathology, National Institute of Mental Health and Neurosciences, Hosur Road, Bengaluru, 560029, India.
Purpose: Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, rapidly growing pigmented neoplasm originating from the neural crest. Predominantly affecting infants, it commonly occurs in the head and neck region. MNTI is often locally aggressive with a high recurrence rate.
View Article and Find Full Text PDFMelanotic neuroectodermal tumor of infancy (MNTI) is a rare distinctive neoplasm of infants with rapid expansile growth and a high rate of recurrence. Most commonly, the lesion affects the maxilla followed by the skull and orbit. One such case was diagnosed in a 5-month-old boy who presented with rapidly enlarged swelling over the back of the skull.
View Article and Find Full Text PDFMelanotic neuroectodermal tumor of infancy: A case report.
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Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. Electronic address:
Operative Technique for Extirpation of Large Melanotic Neuroectodermal Tumor of Infancy Involving Alveolus and Anterior Maxilla in the Region of the Premaxilla.
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Department of Surgery, Division of Plastic Surgery, Nemours Children's Hospital, Wilmington, DE.
Article Synopsis
- * A case study of a 10-week-old boy presented an aggressively growing tumor, leading to a carefully planned surgical resection involving innovative techniques such as a piezoelectric saw to ensure precise removal without damaging surrounding structures.
- * The complete excision of the tumor was successful with negative margins, emphasizing that thorough removal is crucial to prevent recurrence, and demonstrating the advantages of advanced surgical tools for better patient outcomes.
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