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Wealth is health: High economic status in Cameroon correlates with protective gear use in traffic injuries and improved clinical outcomes.
J Trauma Acute Care Surg
January 2025
From the Faculty of Health Sciences (F.N.D.D.), University of Bamenda, Bamenda, Cameroon; Program for the Advancement of Surgical Equity, Department of Surgery (M.T.Y., R.O., S.A.C., C.J.), University of California, Los Angeles, Los Angeles, California; Data Science Center for Surgery, Injury, and Equity in Africa (A.D.T., R.M.); Faculty of Health Sciences (A.C.-M.), University of Buea, Buea, Cameroon; and Division of Biostatistics (A.H.), School of Public Health, University of California, Berkley, California.
Introduction: Africa is the least motorized populated continent, yet it experiences the highest traffic fatality rate. Despite laws mandating helmet and seatbelt use, data on protective gear use among Cameroonian road traffic injury (RTI) patients remains sparse.
Methods: We extracted Cameroon Trauma Registry data prospectively collected from 10 hospitals during July 2022 to December 2023.
Healthcare resource utilization and costs of using Cariprazine as the first versus subsequent adjunctive therapy for major depressive disorder.
J Med Econ
January 2025
AbbVie, North Chicago, IL, USA.
Aim: Inadequate response to antidepressant therapy (ADT) is common in major depressive disorder (MDD); atypical antipsychotic (AA) adjunctive therapy may be effective for these patients. This study aimed to compare healthcare resource utilization (HRU) and costs between patients initiating the AA cariprazine as their first adjunctive therapy vs those initiating cariprazine subsequently.
Methods: The Merative MarketScan® Commercial Database (January 1, 2015, to June 30, 2021) was used to identify US adults with MDD and ≥1 pharmacy claim for cariprazine adjunctive to ADT in 2018 or after.
Mode switching control of independent metering fluid power systems.
ISA Trans
January 2025
State Key Laboratory of Crane Technology, Yanshan University, Qinhuangdao 066004, China. Electronic address:
An independent metering system (IMS) realizes the decoupling of the meter-in and meter-out orifices. The energy efficiency of the hydraulic system can be effectively improved by switching between different operational modes. However, the tracking accuracy of the IMS mode-switching system is difficult to ensure, which can easily lead to instability in the hydraulic system.
View Article and Find Full Text PDF[UPFRONT DOCETAXEL WITH ANDROGEN DEPRIVATION THERAPY IN MALES WITH HIGH-VOLUME METASTATIC CASTRATION-SENSITIVE PROSTATE CANCER: RESULTS OF A SINGLE-INSTITUTION SERIES].
Nihon Hinyokika Gakkai Zasshi
January 2025
Department of Urology, Jikei University of Medicine.
(Objective) This study aimed at evaluating the efficacy and safety of upfront docetaxel (DTX) treatment and androgen deprivation therapy (ADT) in male patients with high-volume metastatic castration-sensitive prostate cancer (HV-mCSPC). (Methods) This retrospective study was conducted using the medical records of 30 patients treated for HV-mCSPC by using upfront DTX treatment along with ADT at Atsugi City Hospital between December 2015 and December 2022. The patient characteristics, demographics, oncological outcomes, adverse events, and sequential therapy were evaluated.
View Article and Find Full Text PDF« Augmented radiotherapy » in the management of high-risk prostate cancer (PCa): A systematic review.
Crit Rev Oncol Hematol
January 2025
Centre de Radiothérapie Charlebourg, La Défense, Groupe Amethyst, 65, avenue Foch, La Garenne-Colombes 92250, France; Department of radiation oncology, Institut Bergonié, Bordeaux, France.
Background: In patients with high-risk (HR) prostate cancer (PCa) treated with radiotherapy and androgen deprivation therapy (ADT), intensification with androgen receptor pathway inhibitor (ARPI) improves overall survival (OS), at the cost of significant side-effects. We hypothesized that "augmented RT" schedules (defined as either dose-escalation on the prostate gland over 78 Gy and/or addition of whole pelvic radiotherapy (WPRT)), combined with long-term ADT can reach excellent prostate cancer specific survival (PCSS) in this population with little detrimental impact on quality of life.
Methods: We searched Pubmed database until February 8, 2024.
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