[Diagnosis and treatment of dorsopathy in patients with connective tissue dysplasia].

Zh Nevrol Psikhiatr Im S S Korsakova

Prof. A. Polenov Research Institute of Neurosurgery, affiliation of V. Almazov North-Western Medical Research Center, St. Petersburg, Russia.

Published: February 2018

Aim: To study the pathogenesis, clinical manifestations and treatment of dorsopathy in patients with connective tissue dysplasia.

Material And Methods: Thirty-six patients, aged from 18 to 45 years, with lumbar-sacral radiculopathies associated with connective tissue dysplasia were examined. Detailed neurological examination, X-ray visualization and MRI of lumbosacral spine section, electromyographic assessment were performed. A five-point scale of neuro-vertebrological symptoms, the Numerical Rating Scale (NRS) and the Roland-Morris Low Back Pain and Disability Questionnaire were used.

Results And Conclusion: The results contained own data on the pathogenesis, clinical manifestations and treatment of dorsopathies in connective tissue dysplasias. Inclusion of long-acting pentoxifylline (vasonite) in the combined therapy in patients with dorsopathy associated with connective tissue dysplasia had a positive effect on disease course, decreased pain intensity and improved life activities.

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http://dx.doi.org/10.17116/jnevro20171177143-46DOI Listing

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