AI Article Synopsis

  • A new compound called Colletotrichine A (1) was isolated from the fungus Colletotrichum gloeosporioides GT-7.
  • The structure of Colletotrichine A was determined using 1D and 2D NMR spectroscopy techniques.
  • The compound demonstrated inhibitory activity against acetylcholinesterase (AChE) with an IC value of 28 μg/mL, suggesting potential therapeutic applications.

Article Abstract

One new compound, Colletotrichine A (1), was produced by the fungal Colletotrichum gloeosporioides GT-7. The structure was established by 1D and 2D NMR spectra. Monoamine oxidase (MAO) and acetylcholinesterase (AChE) inhibitory activity of 1 was also evaluated. Compound 1 showed AChE-inhibiting activity with IC value of 28 μg/mL.

Download full-text PDF

Source
http://dx.doi.org/10.1080/14786419.2017.1365071DOI Listing

Publication Analysis

Top Keywords

colletotrichum gloeosporioides
8
gloeosporioides gt-7
8
colletotrichine sesquiterpenoid
4
sesquiterpenoid colletotrichum
4
gt-7 fungal
4
fungal endophyte
4
endophyte uncaria
4
uncaria rhynchophylla
4
rhynchophylla compound
4
compound colletotrichine
4

Similar Publications

Comparative transcriptome analysis reveals pathogenic mechanisms of Colletotrichum gloeosporioides in figs (Ficus carica L.) infection.

Microb Pathog

January 2025

Key Laboratory of Biology and Sustainable Management of Plant Diseases and Pests of Anhui Higher Education Institutes, Hefei,230036, China; School of Plant Protection, Anhui Agricultural University, Hefei,230036, China. Electronic address:

Colletotrichum gloeosporioides is a pathogen responsible for causing anthracnose in Ficus carica L. (figs) and other fruits worldwide. Various stages of infection have been reported in C.

View Article and Find Full Text PDF

Discovery of New Benzohydrazide Derivatives Containing 4-Aminoquinazoline as Effective Agricultural Fungicides, the Related Mechanistic Study, and Safety Assessment.

J Agric Food Chem

January 2025

State Key Laboratory of Green Pesticides, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang 550025, PR China.

A total of 38 new benzohydrazide derivatives bearing the 4-aminoquinazoline moiety were designed and synthesized based on the active subunit combination approach and tested in detail for their inhibition activities against eight agricultural phytopathogenic fungi. The bioassay results indicated that many of the synthesized compounds exhibited extraordinary fungicidal activities in vitro against the tested fungi. For example, compounds , , , and had EC (half-maximal effective concentration) values of 0.

View Article and Find Full Text PDF

Walnut PR10/Bet v1-like proteins interact with chitinase in response to anthracnose stress.

J Evol Biol

January 2025

Laboratory of Walnut Research Center, College of Forestry, Northwest A & F University, Yangling, 712100 Shaanxi, China.

Walnut is a significant woody oil tree species that has been increasingly affected by anthracnose in recent years. Effective anthracnose control is crucial for walnut yield and quality, which requires a comprehensive understanding of the response mechanisms to Colletotrichum gloeosporioides. The PR10/Bet v1-like proteins are involved in defense against various disease, therefore, in this study, 7 JrBet v1s were identified from the walnut transcriptome (named JrBet v1-1~1-7), whose open reading frame (ORF) was 414~483 bp in length with isoelectric point ranging from 4.

View Article and Find Full Text PDF

Introduction: Grapevine ( L.), one of the economically important fruit crops cultivated worldwide, harbours diverse endophytic bacteria (EBs) responsible for managing various fungal diseases. Anthracnose () (Penz.

View Article and Find Full Text PDF

Dioscorea alata, a key tuber crop for global food security, is threatened by anthracnose disease caused by Colletotrichum gloeosporioides. However, identification of functional resistance genes against C. gloeosporioides in D.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!