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Artificial Intelligence, DNA Mimicry, and Human Health. | LitMetric

Artificial Intelligence, DNA Mimicry, and Human Health.

Med Sci Monit

Department of Psychiatry, Charles University, Center for Molecular and Cognitive Neuroscience, Prague, Czech Republic.

Published: August 2017

The molecular evolution of genomic DNA across diverse plant and animal phyla involved dynamic registrations of sequence modifications to maintain existential homeostasis to increasingly complex patterns of environmental stressors. As an essential corollary, driver effects of positive evolutionary pressure are hypothesized to effect concerted modifications of genomic DNA sequences to meet expanded platforms of regulatory controls for successful implementation of advanced physiological requirements. It is also clearly apparent that preservation of updated registries of advantageous modifications of genomic DNA sequences requires coordinate expansion of convergent cellular proofreading/error correction mechanisms that are encoded by reciprocally modified genomic DNA. Computational expansion of operationally defined DNA memory extends to coordinate modification of coding and previously under-emphasized noncoding regions that now appear to represent essential reservoirs of untapped genetic information amenable to evolutionary driven recruitment into the realm of biologically active domains. Additionally, expansion of DNA memory potential via chemical modification and activation of noncoding sequences is targeted to vertical augmentation and integration of an expanded cadre of transcriptional and epigenetic regulatory factors affecting linear coding of protein amino acid sequences within open reading frames.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566202PMC
http://dx.doi.org/10.12659/msm.906498DOI Listing

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