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| http://dx.doi.org/10.1007/s00401-017-1763-1 | DOI Listing |
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Clinical characteristics and detection of MYB-QKI fusions in patients with angiocentric glioma.
Neurol Sci
January 2025
Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, No. 50, Yikesong, Xiangshan, Haidian District, Beijing, 100093, China.
Purpose: Angiocentric glioma (AG), a benign tumor identified within the last two decades, was officially included in the 2007 WHO Classification of Tumors of the Central Nervous System, WHO grade I. The tumor is relatively rare, with only approximately 100 cases reported. We aim to complement the characteristics and long-term prognosis of AG, as well as to detect MYB-QKI fusions.
View Article and Find Full Text PDFCase Report: Brainstem angiocentric glioma presenting in a toddler child-diagnostic and therapeutic challenges.
Pathol Oncol Res
June 2023
Department of Clinical Neuropathology, King's College Hospital, London, United Kingdom.
Angiocentric gliomas (AG) in brainstem location are exceedingly rare and might cause differential diagnostic problems and uncertainty regarding the best therapeutic approach. Hereby, we describe the clinicopathological findings in a brainstem AG presenting in a toddler child and review the literature. A 2-year-old boy presented with 5 weeks history of gait disturbances, frequent falls, left-sided torticollis and swallowing problems.
View Article and Find Full Text PDFNeuroimaging features of angiocentric glioma: A case series and systematic review.
J Neuroimaging
May 2022
Division of Neuroradiology, Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.
Background And Purpose: Angiocentric gliomas (AGs) are epileptogenic low-grade gliomas in young patients. We aimed to investigate the MRI findings of AGs and systematically review previous publications and three new cases.
Methods: We searched PubMed, Elsevier's abstract and citation database, and Embase databases and included 50 patients with pathologically proven AGs with analyzable preoperative MRI including 3 patients from our institution and 47 patients from 38 publications (median age, 13 years [range, 2-83 years]; 35 men).
Article Synopsis
- Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids is an inflammatory syndrome that affects multiple brain structures, presenting with various neurological symptoms like ataxia and dysarthria, which complicates diagnosis due to their episodic nature.
- A case study of a 74-year-old man revealed that his symptoms were linked to brain lesions showing T-cell infiltration, while also having a diagnosis of primary lung cancer.
- Treatment with high-dose glucocorticoids led to significant clinical and radiographic improvement, underscoring the importance of recognizing this syndrome despite its diagnostic challenges.*
Angiocentric glioma of brainstem.
Neurosciences (Riyadh)
October 2020
Neuroscience Department, King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia. E-mail:
Angiocentric glioma is a rare brain tumor commonly found in frontal or temporal lobes. It has a benign course, and surgical resection can be curative. Brainstem location is extremely rare, with only six cases reported so far in the literature.
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