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| http://dx.doi.org/10.1016/j.bbi.2017.08.007 | DOI Listing |
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Transcranial Direct Current Stimulation to Provide Neuroprotection and Enhance Cerebral Blood Flow in Stroke: A Comprehensive Review.
Medicina (Kaunas)
December 2024
Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Stroke remains a leading cause of global disability and mortality despite advancements in acute interventions. Transcranial direct current stimulation (tDCS), a non-invasive neuromodulation technique, has primarily been studied for its effects on cortical excitability, with limited exploration of its neuroprotective and hemodynamic benefits. This review examines the role of tDCS in stroke, with a focus on neuroprotection in acute settings and cerebral blood flow (CBF) modulation in both acute and chronic phases.
View Article and Find Full Text PDFNeuromodulation Strategies in Lifelong Bipolar Disorder: A Narrative Review.
Behav Sci (Basel)
December 2024
Department of Public Health and Infectious Diseases, Sapienza University of Rome, Piazza Aldo Moro, 100165 Rome, Italy.
Bipolar disorder is a debilitating psychiatric condition characterized by recurrent episodes of mania and depression, affecting millions worldwide. While pharmacotherapy remains the cornerstone of treatment, a significant proportion of patients exhibit inadequate response or intolerable side effects to conventional medications. In recent years, neuromodulation techniques have emerged as promising adjunctive or alternative treatments for bipolar disorder.
View Article and Find Full Text PDFModulating delirium through stimulation (MoDeSt): study protocol for a randomized, double-blind, sham-controlled trial assessing the effect of postoperative transcranial electrical stimulation on delirium incidence.
Trials
January 2025
Department of Neurology, Universitätsmedizin Greifswald, Fleischmannstraße 6, Greifswald, 17489, Germany.
Background: Postoperative delirium (POD) is the most common neurological adverse event among elderly patients undergoing surgery. POD is associated with an increased risk for postoperative complications, long-term cognitive decline, an increase in morbidity and mortality as well as extended hospital stays. Delirium prevention and treatment options are currently limited.
View Article and Find Full Text PDFThe effect of transcranial Direct Current Stimulation on the Iowa Gambling Task: a scoping review.
Front Psychol
December 2024
Department of Psychology, Università Cattolica del Sacro Cuore, Milan, Italy.
Article Synopsis
- The Iowa Gambling Task (IGT) is an effective method for studying decision-making processes by providing feedback on choices, and its study has recently incorporated transcranial direct current stimulation (tDCS) to explore cognitive and neural mechanisms.
- A scoping review found that tDCS could improve IGT performance, particularly highlighting the importance of the dorsolateral prefrontal cortex and orbitofrontal cortex in making risky or ambiguous decisions.
- The findings suggest that tDCS can enhance decision-making in both healthy individuals and patients, indicating its potential application in daily decisions and emphasizing the need for further research into the underlying mechanisms.
Postoperative cognitive dysfunction in elderly postcardiac surgery patients: progress in rehabilitation application research.
Front Rehabil Sci
December 2024
Nursing Department, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Article Synopsis
- Postoperative cognitive dysfunction (POCD) is a common issue in elderly patients after cardiac surgery, primarily influenced by factors like age and preoperative cognitive levels.
- Causes of POCD include cerebral microembolism, neuroinflammation, and strokes that may not have clear origins.
- Effective rehabilitation strategies—such as cognitive training, exercise, acupuncture, and new technologies like virtual reality—are vital for improving cognitive outcomes in these patients.
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