AI Article Synopsis
- Researchers used silver nanoparticles (AgNPs) as a catalyst to quickly turn HAuCl into a stable gold nanoparticle solution (Ag/AuNP) that enhances Raman scattering when combined with Victoria blue 4R (VB4r) probes.
- Chondroitin sulfate (Chs) interacts with VB4r probes, causing a measurable decrease in SERS signal, which decreases linearly with Chs concentration in the range of 3.1-500 ng/ml.
- This method allows for a sensitive and straightforward way to quantitatively analyze Chs in real samples, achieving a low detection limit of 1.0 ng/ml, a relative standard deviation of 1.47-3.16%, and a
Article Abstract
Using silver nanoparticles (AgNPs) as the nanocatalyst, l-cysteine rapidly reduced HAuCl to make a stable gold nanoparticle sol (Ag/AuNP) that had a high surface-enhanced Raman scattering (SERS) activity in the presence of Victoria blue 4R (VB4r) molecular probes. Under the selected conditions, chondroitin sulfate (Chs) reacted with the VB4r probes to form associated complexes that caused the SERS effect to decrease to 1618 cm . The decreased SERS intensity was linear to the Chs concentration in the range 3.1-500 ng/ml, with a detection limit of 1.0 ng/ml Chs. Accordingly, we established a simple and sensitive SERS quantitative analysis method to determine Chs in real samples, with a relative standard deviation of 1.47-3.16% and a recovery rate of 97.6-104.2%.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/bio.3382 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!