The current study investigated whether children's mental representations of numbers are organized spatially at the onset of formal schooling using a manual-pointing task. First-graders (N = 77) saw four numbers (1, 3, 7, 9) presented randomly in four spatial positions (extreme left, left, right, extreme right) on a touch screen. In a Go/No-Go task, children were asked to press the appearing numbers as fast and accurately as possible, but only when the numbers were "smaller" (or "larger" in a different block) than 5. Results indicated that response times were significantly affected by the spatial position in which the different numbers were presented. Response times for small numbers (1 and 3) increased and response times for large numbers (7 and 9) decreased, the more they were presented towards the right side of the screen. These findings suggested that first-graders spontaneously employed a spatial number representation that was oriented from left to right. Furthermore, this left-to-right organization could not be easily changed by priming a different direction. Our findings indicate that even young children map numbers continuously onto space.
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January 2025
School of Physics and Materials Science, Nanchang University, Nanchang, Jiangxi, 330031, China.
As emerging cutting-edge energy storage technologies, aqueous zinc-ion batteries (AZIBs) have garnered extensive research attention for its high safety, low cost, abundant raw materials, and, eco-friendliness. Nevertheless, the commercialization of AZIBs is mainly limited by insufficient development of cathode materials. Among potential candidates, MXene-based materials stand out as a promising option for their unique combination of hydrophilicity and conductivity.
View Article and Find Full Text PDFEur J Sport Sci
January 2025
Graduate Program in Human Movement Sciences, Institute of Health Sciences, Federal University of Pará, Belem, Brazil.
Executive functioning (EF) in referees is associated with their decision-making during a match and can be affected by mental fatigue (MF), a psychobiological state induced by prolonged periods of cognitive activity or high cognitive demand within a short timeframe. Therefore, the aim of this study was to investigate the impact of MF on EF and the perception of effort during a physical task for football referees. Twelve male professional football referees were recruited (32 ± 7.
View Article and Find Full Text PDFJ Clin Microbiol
January 2025
Laboratory of Animal Pathology and Public Health, National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Unlabelled: Hepatitis E virus (HEV) is a globally prevalent zoonotic pathogen that is primarily spread through the fecal-oral route, such as by consuming undercooked or contaminated pork. HEV infection leads to an estimated 3.3 million symptomatic cases of viral hepatitis and 70,000 deaths in human populations each year.
View Article and Find Full Text PDFImmun Inflamm Dis
January 2025
Second Department of Oncology, Guangdong Second Provincial General Hospital, Guangzhou, China.
Background: SET domain-containing protein 4 (SETD4) is a histone methyltransferase that has been shown to modulate cell proliferation, differentiation, and inflammatory responses by regulating histone H4 trimethylation (H4K20me3). Previous reports have demonstrated its function in the quiescence of cancer stem cells as well as drug resistance in several cancers. A limited number of systematic studies have examined SETD4's role in the tumor microenvironment, pathogenesis, prognosis, and therapeutic response.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
National Center for International Research on Green Optoelectronics, Guangdong Provincial Key Laboratory of Optical Information Materials and Technology, Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou 510006, China.
Ice melting, a common yet complex phenomenon, remains incompletely understood. While theoretical studies suggest that preexisting defects in ice generate "off-lattice" water molecules, triggering bulk ice melting, direct experimental evidence of their form has been lacking as the transparent and transient nature of ice poses significant challenges for observation with current techniques. Here, we introduce an ice-melting-induced lyophilization (IMIL) technique that employs graphene-based nanoprobes to replicate and track liquid evolution within melting bulk ice.
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