Non-Hermitian degeneracies, also known as exceptional points, have recently emerged as a new way to engineer the response of open physical systems, that is, those that interact with the environment. They correspond to points in parameter space at which the eigenvalues of the underlying system and the corresponding eigenvectors simultaneously coalesce. In optics, the abrupt nature of the phase transitions that are encountered around exceptional points has been shown to lead to many intriguing phenomena, such as loss-induced transparency, unidirectional invisibility, band merging, topological chirality and laser mode selectivity. Recently, it has been shown that the bifurcation properties of second-order non-Hermitian degeneracies can provide a means of enhancing the sensitivity (frequency shifts) of resonant optical structures to external perturbations. Of particular interest is the use of even higher-order exceptional points (greater than second order), which in principle could further amplify the effect of perturbations, leading to even greater sensitivity. Although a growing number of theoretical studies have been devoted to such higher-order degeneracies, their experimental demonstration in the optical domain has so far remained elusive. Here we report the observation of higher-order exceptional points in a coupled cavity arrangement-specifically, a ternary, parity-time-symmetric photonic laser molecule-with a carefully tailored gain-loss distribution. We study the system in the spectral domain and find that the frequency response associated with this system follows a cube-root dependence on induced perturbations in the refractive index. Our work paves the way for utilizing non-Hermitian degeneracies in fields including photonics, optomechanics, microwaves and atomic physics.
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http://dx.doi.org/10.1038/nature23280 | DOI Listing |
Adv Mater
January 2025
Key Lab of Artificial Micro- and Nano-Structures of Ministry of Education of China, School of Physics and Technology, Wuhan University, Wuhan, 430072, China.
Porous lead iodide (PbI) film is crucial for the complete reaction between PbI and ammonium salts in sequential-deposition technology so as to achieve high crystallinity perovskite film. Herein, it is found that the tensile stress in tin (IV) oxide (SnO) electron transport layer (ETL) is a key factor influencing the morphology and crystallization of PbI films. Focusing on this, lithium trifluoromethanesulfonate (LiOTf) is used as an interfacial modifier in the SnO/PbI interface to decrease the tensile stress to reduce the necessary critical Gibbs free energy for PbI nuclei formation.
View Article and Find Full Text PDFNanophotonics
January 2025
Department of Electronic Engineering, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
Topological insulators and bound states in the continuum represent two fascinating topics in the optical and photonic domain. The exploration of their interconnection and potential applications has emerged as a current research focus. Here, we investigated non-Hermitian photonics based on a parallel cascaded-resonator system, where both direct and indirect coupling between adjacent resonators can be independently manipulated.
View Article and Find Full Text PDFCase Rep Genet
January 2025
Medical Investigation of Neurodevelopmental Disorders (MIND) Institute, University of California, 2825 50th Street, Davis, Sacramento 95817, California, USA.
Fragile X syndrome (FXS) presents with autism spectrum disorder (ASD), intellectual disability, developmental delay, seizures, hypotonia during infancy, joint laxity, behavioral issues, and characteristic facial features. The predominant mechanism is due to CGG trinucleotide repeat expansion of more than 200 repeats in the 5'UTR (untranslated region) of (Fragile X Messenger Ribonucleoprotein 1) causing promoter methylation and transcriptional silencing. However, not all patients presenting with the characteristic phenotype and point/frameshift mutations with deletions in have been described in the literature.
View Article and Find Full Text PDFQuant Imaging Med Surg
January 2025
Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Background: Echocardiography can conveniently, rapidly, and economically evaluate the structure and function of the heart, and has important value in the diagnosis and evaluation of cardiovascular diseases (CVDs). However, echocardiography still exhibits significant variability in image acquisition and diagnosis, with a heavy dependency on the operator's experience. Image quality affects disease diagnosis in the later stage, and even image quality assessment still has variability in human evaluation.
View Article and Find Full Text PDFAnal Methods
January 2025
Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, PR China.
Methotrexate (MTX), a widely administered medication for treating an array of tumors and autoimmune disorders, necessitates stringent monitoring due to the potential for severe adverse effects associated with its high dosage. Nevertheless, the existing methods for monitoring MTX are often intricate, time-consuming and incur significant costs. In this work, we constructed a controlled release sensor, harnessing the versatility of a personal glucose meter (PGM), which had been devised for the swift detection of MTX.
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