This paper aims to analyse changes in the retail pharmaceutical market following policy changes in the Farmácia Popular Program (FP), a medicines subsidy program in Brazil. The retrospective longitudinal analyses focus on therapeutic class of agents acting on the renin-angiotensin system. Data obtained from QuintilesIMS (formerly IMS Health) included private retail pharmacy sales volume (pharmaceutical units) and sales values from 2002 to 2013. Analyses evaluated changes in market share following key FP policy changes. The therapeutic class was selected due to its relevance to hypertension treatment. Market share was analysed by therapeutic sub-classes and by individual company. Losartan as a single product accounted for the highest market share among angiotensin II antagonists. National companies had higher sales volume during the study period, while multinational companies had higher sales value. Changes in pharmaceutical market share coincided with the inclusion of specific products in the list of medicines covered by FP and with increases in or exemption from patient copayment.
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http://dx.doi.org/10.1590/1413-81232017228.01442017 | DOI Listing |
PLoS One
January 2025
Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.
Epithelial cancers are typically heterogeneous with primary prostate cancer being a typical example of histological and genomic variation. Prior studies of primary prostate cancer tumour genetics revealed extensive inter and intra-patient genomic tumour heterogeneity. Recent advances in machine learning have enabled the inference of ground-truth genomic single-nucleotide and copy number variant status from transcript data.
View Article and Find Full Text PDFPLoS One
January 2025
School of Economics and Management, Tongji University, Shanghai, China.
Centralized drug procurement is a common practice worldwide to relieve the healthcare burden and promote high-quality development in the pharmaceutical industry. However, scholars have not yet reached an agreement on whether centralized procurement can facilitate the innovation activities of pharmaceutical firms. China's centralized volume-based procurement (CVBP) implemented in 2018 provides an ideal quasi-natural experiment to evaluate the effect of centralized procurement on the R&D investment of the firms.
View Article and Find Full Text PDFSci Rep
January 2025
College of Architecture and Civil Engineering, Xinyang Normal University, Xinyang, 464000, China.
The use of green buildings is an inevitable requirement for sustainable development. However, green buildings face the awkward situation of a slow market share increase. This study explores the changing strategies of government and developers in promoting green buildings and how they affect consumer acceptance, providing an interdisciplinary theory for promoting green buildings.
View Article and Find Full Text PDFPLOS Glob Public Health
January 2025
Health Division, ASEAN Secretariat, Jakarta, Indonesia.
PLoS One
January 2025
Business School of Sichuan Normal University, Chengdu, Sichuan Province, China.
This study examines the influence of executives' accounting competence on relationship between goodwill impairment signal and goodwill impairment, considering the perspective of performance compensation commitment. The research employs an empirical research method and utilizes a sample of A-share listed companies in China that have signed performance compensation commitment agreements from 2007 to 2022. I found that the executives' accounting competence weakens the relationship between goodwill impairment signal and goodwill impairment.
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