AI Article Synopsis
- The study analyzes how various clinical and biochemical factors influence the effectiveness of lower limb artery stenting in patients.
- The research involved evaluating the medical records of 91 patients who underwent stenting and were followed for at least one year.
- Key findings revealed that factors like age, dyslipidemia, and blood parameters significantly impact the risk of stent failure, highlighting the need for further investigations on dyslipidemia’s role in treatment outcomes.
Article Abstract
Background: The outcome of endovascular therapy can be influenced by a number of factors, either demographic, biochemical, angiographic or procedural. Knowledge about these factors may help in the individualization of therapeutic methods, surveillance intensity, and should, ultimately, improve intervention efficacy.
Objectives: The aim of this study was to estimate the effect of clinical and biochemical factors on the late outcome of lower limb artery stenting.
Material And Methods: The medical documentation of 91 patients with at least a 1 year follow-up after the stenting of a lower limb artery was retrospectively evaluated. Uniand multivariate analyses were performed.
Results: Primary patency within an approximately 1.5-year follow-up amounted to 68.2%. The probability of freedom from target lesion revascularization was significantly greater in patients with dyslipidemia. According to the Cox proportional-hazards analysis, the risk of target extremity revascularization was significantly affected by the following (hazard ratio [HR], 95% confidence interval): Age (0.93, 0.88-0.99); dyslipidemia at inclusion (0.046, 0.01-0.23); LDL blood concentration (1.02; 1.01-1.04); hematocrit (1.2, 1.02-1.42); mean platelet volume (0.66, 0.44-0.99); INR (1.58, 1.13-2.21); and aPTT (1.18, 1.07-1.3).
Conclusions: Endovascular treatment with stenting in patients with atherosclerotic peripheral arterial disease is effective, but the risk of primary patency loss was affected by the presence of dyslipidemia, age, and blood coagulation parameters. The effect of dyslipidemia on stent failure occurrence should be evaluated in further studies.
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| http://dx.doi.org/10.17219/acem/58997 | DOI Listing |
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