We report two cases in which an internal mammary artery graft was found to be nonfunctional in the early postoperative period, but repeat catheterization at 6 months revealed the graft to be patent. These two cases substantiate that closure of an internal mammary artery graft may be reversible.
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Cancer Commun (Lond)
January 2025
Department of Medical Oncology, Cancer Hospital, Harbin Medical University, Harbin, Heilongjiang, P. R. China.
Background: The standard first-line treatment for human epidermal growth factor receptor 2 (HER2)-positive recurrent/metastatic breast cancer currently includes pertuzumab plus trastuzumab and docetaxel. This study aimed to evaluate the effectiveness of KN026, an anti-HER2 bispecific antibody, plus docetaxel in first-line treatment of HER2-positive recurrent/metastatic breast cancer.
Methods: This open-label, single-arm, phase II study enrolled patients with HER2-positive recurrent/metastatic breast cancer in 19 centers across China from December 30, 2019 to May 27, 2021.
Clin Breast Cancer
December 2024
Medical Oncology and Palliative Care, Department of Medicine, Breast Cancer Disease Oriented Team, University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792-3252.
Background: The SMILE study is a multi-institutional phase II clinical trial to determine the efficacy and safety of an antiprogestin, onapristone, in combination with fulvestrant as second-line therapy for patients with ER+, PgR+/-, HER2- metastatic breast cancer. This study was terminated early and herein, we report patient characteristics, and outcomes.
Methods: Eligibility criteria included disease progression on ≥2 lines of prior therapy, ECOG performance status ≤ 2, measurable disease per RECIST 1.
JAAD Case Rep
November 2024
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Plast Reconstr Surg Glob Open
January 2025
From the Section General Internal Medicine, Department of Internal Medicine, Amsterdam Public Health Research Institute, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Background: Explantation often alleviates symptoms in women with breast implant illness. However, persistent complaints in some cases may be linked to persistent silicone-induced inflammation from residual silicone particles. Positron emission tomography (PET) imaging could potentially detect this inflammation.
View Article and Find Full Text PDFIndian J Thorac Cardiovasc Surg
February 2025
Department of Cardiovascular & Thoracic Surgery, Government Medical College, Kottayam, Kerala India.
In coronary artery bypass grafting (CABG), the use of the left internal mammary artery (LIMA) is considered the gold standard. The conventional technique of using electrocautery for LIMA harvesting is associated with adverse events. In this study, we used a different technique that combined carbon dioxide with electrocautery to harvest LIMA and compared it with the conventional electrocautery method.
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