Background: The decision to test for the etiology of diarrhea is a challenging question for practicing pediatricians.
Methods: The main goal of this retrospective cohort study was to identify factors associated with testing for and diagnosis of rotavirus, , or other bacterial infections, as well as the length of stay (LOS) for children with acute gastroenteritis who were hospitalized at a single institution. Patients aged 6 to 60 months with acute diarrhea (<14 days) and no underlying gastrointestinal conditions were included. Data were analyzed by using multivariate logistic and linear regression models.
Results: Stool testing was performed in 73.1% of the 331 patients studied. The majority were tested for multiple pathogens, including rotavirus (65.9%), (30.8%), and other bacteria (63.4%), with recovery rates of 33.0%, 9.8%, and 6.7%, respectively. Rotavirus was more often identified in older patients with dehydration and vomiting. Although testing for was more likely with prolonged diarrhea, no vomiting, and recent antibiotic use, no factors were associated with recovery. Patients who were diagnosed with were more likely to receive probiotics than those who received negative test results. LOS was not associated with stool testing or recovery of any tested pathogens.
Conclusions: Although children with acute gastroenteritis underwent frequent stool testing for diarrheal etiology, detection of a pathogen was uncommon and not associated with a change in LOS. Experimental research will be needed to make additional conclusions about the efficacy of testing for diarrheal etiology in the inpatient practice of acute pediatric diarrhea.
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http://dx.doi.org/10.1542/hpeds.2016-0180 | DOI Listing |
Grimontia hollisae, an uncommon cause of sepsis, was identified in a 9-month-old infant in Africa without confirmed seafood consumption. Prompt diagnosis through blood culture and targeted antibiotic therapy ensured recovery, emphasizing the need for increased awareness, enhanced diagnostic tools, and active monitoring of emerging pathogens in tropical and resource-limited regions. We present a case report involving a 9-month-old infant who exhibited symptoms of acute gastroenteritis.
View Article and Find Full Text PDFGenome Med
December 2024
Department of Medical and Surgical Sciences, Digestive Diseases Centre (CEMAD), Policlinico Universitario "A. Gemelli" Foundation, IRCCS, Rome, Italy.
Diverticular disease (DD) is widespread worldwide. The role of gut microbiota (GM) in DD is not entirely understood. Here we discuss the significance of the current knowledge on GM in the different stages of DD and how crucial these acquisitions are for designing diagnostic and therapeutic trials in this field.
View Article and Find Full Text PDFPol J Vet Sci
December 2024
Department of Pathology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, 15030, İstiklal Campus, Burdur, Turkey.
Acute ulcerative colitis is an inflammatory disease of the colon that is becoming increasingly prevalent. Yet, a growing body of evidence supports the efficacy of dietary interventions in preventing acute ulcerative colitis. Fermented beverages have been the focus of research in humans and animals for several years due to their potential to influence overall health functions with an emphasis on gut health.
View Article and Find Full Text PDFVaccine
December 2024
ICMR- National Institute for Research in Bacterial Infections (formerly ICMR-NICED), Kolkata, India. Electronic address:
Background: Despite global rotavirus vaccination efforts, rotavirus remains a leading cause of childhood deaths from acute gastroenteritis. Post-vaccination studies in India, particularly in eastern India, have been limited, despite high prevalence of rotavirus in this region prior to vaccine introduction. This study was conducted to assess the impact of rotavirus vaccine on the epidemiology of rotavirus and other enteric viruses, as well as the changes in the diversity of rotavirus strains among children (≤5 years) with acute gastroenteritis.
View Article and Find Full Text PDFVet Sci
December 2024
Department of Virology, Croatian Veterinary Institute, 10000 Zagreb, Croatia.
Acute gastroenteritis (AGE) in cattle significantly impacts the economy due to relatively high morbidity and mortality and decreased production. Its multifactorial nature drives its global persistence, involving enteric viruses, bacteria, protozoa, and environmental factors. Bovine (BoRVA) and bovine coronavirus (BCoV) are among the most important enteric RNA viruses causing AGE in cattle.
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