Selective amplifications of LP fundamental mode and higher order modes LP and LP are demonstrated in a double-pass Nd-doped LMA fiber amplifier operating at 910 nm. A multimode core fiber Bragg grating is employed to select a single guided mode by simply adjusting the wavelength of the seed signal. Although the M parameter of the output beam from the amplifier was ~2.5 in a single-pass configuration, a double-pass configuration with LP mode selection reduces the value of the M parameter to 1.06 in spite of the multimode nature of the core (V~5). In addition, it is shown that this amplifier configuration permits to lower both the power saturation and the parasitic emission at 1060 nm, which consequently increase the pump-to-signal conversion efficiency at 910 nm.
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http://dx.doi.org/10.1364/OE.25.018314 | DOI Listing |
Am J Speech Lang Pathol
January 2025
Department of Speech and Hearing Science, The Ohio State University, Columbus.
Purpose: Vocabulary access is important for individuals who use augmentative and alternative communication (AAC), especially for children in the early stages of language learning. This study sought to understand how accurate speech-language pathologists (SLPs), teachers, and parents are in predicting the vocabulary needed by early symbolic communicators who use AAC in three contexts.
Method: Ten groups, each with a child who used AAC as their primary mode of communication and who was classified as an early symbolic communicator and their parent, teacher, and SLP, participated.
J Clin Microbiol
January 2025
Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Higashimurayama, Tokyo, Japan.
, a slow-growing nontuberculous mycobacterium, causes Buruli ulcer, a neglected tropical disease. Distinguishing from related species, including , poses challenges with respect to making accurate identifications. In this study, we developed a rapid and simple identification method based on mycobacterial lipid profiles and used matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) to analyze the lipid profiles of ( = 35) and ( = 19) isolates.
View Article and Find Full Text PDFUnlabelled: The impact of cancer driving mutations in regulating immunosurveillance throughout tumor development remains poorly understood. To better understand the contribution of tumor genotype to immunosurveillance, we generated and validated lentiviral vectors that create an epi-allelic series of increasingly immunogenic neoantigens. This vector system is compatible with autochthonous Cre-regulated cancer models, CRISPR/Cas9-mediated somatic genome editing, and tumor barcoding.
View Article and Find Full Text PDFis the most common cause of life-threatening fungal infection in the developed world but remains a therapeutic challenge. Protein kinases have been rewarding drug targets across diverse indications but remain untapped for antifungal development. Previously, screening kinase inhibitors against revealed a 2,3-aryl-pyrazolopyridine, GW461484A (GW), which targets casein kinase 1 (CK1) family member Yck2.
View Article and Find Full Text PDFPsychol Res Behav Manag
January 2025
School of Basic Medicine, Jining Medical University, Jining, 272067, People's Republic of China.
Purpose: Stressful life events are risk factors of depression. To explore whether the avoidant personality disorder (AVPD) features play a mediating role between stressful life events (SLEs) and depression among Chinese first-year university students.
Methods: The cross-sectional study was conducted from April to October 2018.
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