AI Article Synopsis

  • The precise localization of a single optical emitter is crucial for applications like particle tracking and super resolution microscopy, but traditional microscope techniques face limitations due to photon count.
  • A grating interferometer can enhance the localization of emitters under specific conditions by introducing interference fringes.
  • The study explores methods to further enhance localization precision beyond what the grating interferometer can provide.

Article Abstract

The ability to localize precisely a single optical emitter is important for particle tracking applications and super resolution microscopy. It is known that for a traditional microscope the ability to localize such an emitter is limited by the photon count. Here we analyze the ability to improve such localization by imposing interference fringes. We show here that a simple grating interferometer can introduce such improvement in certain circumstances and analyze what is required to increase the localization precision further.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557332PMC
http://dx.doi.org/10.1364/OE.25.017174DOI Listing

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