Cloxacillin, a semisynthetic penicillin is a potent inhibitor of most penicillinase-producing Staphylococci. Use of high doses of Cloxacillin for 6 weeks is recommended for the treatment of infective endocarditis caused by methicillin-susceptible Staphylococcus aureus (MSSA). Here, we report a case of Cloxacillin-induced agranulocytosis in a patient treated for MSSA native tricuspid valve endocarditis, which was resolved after discontinuation of the antibiotic. This case report highlights a rare adverse event of a commonly used antibiotic.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815267 | PMC |
| http://dx.doi.org/10.1177/0394632017724320 | DOI Listing |
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