In this study we evaluated whether a method of direct location is an appropriate response method for measuring auditory distance perception of far-field sound sources. We designed an experimental set-up that allows participants to indicate the distance at which they perceive the sound source by moving a visual marker. We termed this method Cross-Modal Direct Location (CMDL) since the response procedure involves the visual modality while the stimulus is presented through the auditory modality. Three experiments were conducted with sound sources located from 1 to 6 m. The first one compared the perceived distances obtained using either the CMDL device or verbal report (VR), which is the response method more frequently used for reporting auditory distance in the far field, and found differences on response compression and bias. In Experiment 2, participants reported visual distance estimates to the visual marker that were found highly accurate. Then, we asked the same group of participants to report VR estimates of auditory distance and found that the spatial visual information, obtained from the previous task, did not influence their reports. Finally, Experiment 3 compared the same responses that Experiment 1 but interleaving the methods, showing a weak, but complex, mutual influence. However, the estimates obtained with each method remained statistically different. Our results show that the auditory distance psychophysical functions obtained with the CMDL method are less susceptible to previously reported underestimation for distances over 2 m.
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Eur Arch Otorhinolaryngol
January 2025
Department of Radiology, Istanbul Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Purpose: Cochlear implantation (CI) surgery is essential for restoring hearing in individuals with severe sensorineural hearing loss. Accurate placement of the electrode within the cochlea is essential for successful auditory outcomes and minimizing complications. This study aims to analyze the relationship between the round window niche (RWN) alignment, its visibility during surgery, and the impact on surgical techniques and outcomes.
View Article and Find Full Text PDFMol Ther
January 2025
Institute of Experimental Medicine CAS, Department of Neuroregeneration, Videnska 1083, 142 20, Prague, Czech Republic. Electronic address:
Neurons in the central nervous system (CNS) lose regenerative potential with maturity, leading to minimal corticospinal tract (CST) axon regrowth after spinal cord injury (SCI). In young rodents, knockdown of PTEN, which antagonises PI3K signalling by hydrolysing PIP3, promotes axon regeneration following SCI. However, this effect diminishes in adults, potentially due to lower PI3K activation leading to reduced PIP3.
View Article and Find Full Text PDFJ Acoust Soc Am
December 2024
Key Laboratory of Speech Acoustics and Content Understanding, Institute of Acoustics, Chinese Academy of Sciences, Beijing 100190, China.
Given the substantial time and complexity involved in the perceptual evaluation of head-related transfer function (HRTF) processing, there is considerable value in adopting numerical assessment. Although many numerical methods have been introduced in recent years, monaural spectral distance metrics such as log-spectral distortion (LSD) remain widely used despite their significant limitations. In this study, listening tests were conducted to investigate the correlation between LSD and the auditory perception of HRTFs.
View Article and Find Full Text PDFHear Res
December 2024
Bionics Institute, Fitzroy, Victoria, Australia; Medical Bionics Department, The University of Melbourne, Parkville, Victoria, Australia.
Originally reserved for those who are profoundly deaf, cochlear implantation is now common for people with partial hearing loss, particularly when combined with a hearing aid. This combined intervention enhances speech comprehension and sound quality when compared to electrical stimulation alone, particularly in noisy environments, but the physiological basis for the benefits is not well understood. Our long-term aim is to elucidate the underlying physiological mechanisms of this improvement, and as a first step in this process, we have investigated in normal hearing cats, the degree to which the patterns of neural activity evoked in the inferior colliculus (IC) by speech sounds in various levels of noise allows discrimination between those sounds.
View Article and Find Full Text PDFElife
December 2024
Institute for Systems Research, University of Maryland, College Park, United States.
Perception can be highly dependent on stimulus context, but whether and how sensory areas encode the context remains uncertain. We used an ambiguous auditory stimulus - a tritone pair - to investigate the neural activity associated with a preceding contextual stimulus that strongly influenced the tritone pair's perception: either as an ascending or a descending step in pitch. We recorded single-unit responses from a population of auditory cortical cells in awake ferrets listening to the tritone pairs preceded by the contextual stimulus.
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