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Does Clostridium Perfringens Epsilon Toxin Mimic an Auto-Antigen Involved in Multiple Sclerosis?
Toxins (Basel)
January 2025
Unité des Toxines Bactériennes, Institut Pasteur, Université Paris Cité, CNRS UMR 2001 INSERM U1306, 75015 Paris, France.
Multiple sclerosis (MS) is a chronic immune-mediated neurological disorder, characterized by progressive demyelination and neuronal cell loss in the central nervous system. Many possible causes of MS have been proposed, including genetic factors, environmental triggers, and infectious agents. Recently, epsilon toxin (ETX) has been incriminated in MS, based initially on the isolation of the bacteria from a MS patient, combined with an immunoreactivity to ETX.
View Article and Find Full Text PDFControl of Neonatal Diarrhea in Piglets with Reduced Antibiotic Use by Application of a Complementary Feed-A Randomized Controlled Farm Trial.
Vet Sci
January 2025
Pedersen Nutrition, Ltd., Shaftesbury GB-SP7 9QG, UK.
The objective of this farm trial was to investigate if the consumption of antibiotics could be reduced when piglets showing early signs of neonatal diarrhea were treated with an oral dose of tannin extract derived from sweet chestnut wood. The farm had a very high incidence of neonatal diarrhea among gilt litters. Gilts were randomized into test or control groups in a 1:1 ratio to compare the consumption of antibiotics used for piglets and piglet mortality during the four-week trial period.
View Article and Find Full Text PDFFecal microbiota changes associated with pathogenic and non-pathogenic diarrheas in foals.
BMC Res Notes
January 2025
Department of Animal Science, University of California Davis, 2251 Meyer Hall, One Shields Ave, Davis, CA, 95616, USA.
Objectives: Diarrhea is a common disease that could threaten the welfare of newborn foals. While there are several forms of foal diarrhea, the etiologies can be considered known pathogenic or non-pathogenic in nature. Moreover, there are likely differences in the composition of microbial populations in the gastrointestinal tracts of foals depending upon the etiology of diarrhea.
View Article and Find Full Text PDFMicrobial seafood safety assessment following a marine mucilage disaster in the Sea of Marmara.
Environ Microbiol Rep
February 2025
Faculty of Engineering, Department of Chemistry, Istanbul University-Cerrahpaşa, Istanbul, Türkiye.
Marine mucilage disasters, primarily caused by global warming and marine pollution, threaten food security and the sustainability of marine food resources. This study assessed the microbial risks to public health in common sole, deep-water rose shrimp, European anchovy, Atlantic horse mackerel and Mediterranean mussel following the mucilage disaster in the Sea of Marmara in 2021. The total viable count, total Enterobacteriaceae count and the presence of Escherichia coli O157:H7, Salmonella spp.
View Article and Find Full Text PDFCharacterization of bioaerosol exposures in wastewater treatment plant workers and serum levels of lung and inflammatory markers.
J Hazard Mater
January 2025
The National Research Centre for the Working Environment, Lersø Parkallé 105, Copenhagen 2100, Denmark. Electronic address:
Wastewater treatment plant (WWTP) workers are exposed to bioaerosols containing bacteria, fungi, and endotoxin, potentially posing health risks to workers. This study quantified personal exposure levels to airborne bacteria and fungi, endotoxin, and dust among 44 workers during two seasons at four WWTPs. Associations between the exposure measurements and serum levels of biomarkers CRP, SAA, and CC16 were also assessed.
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