Postoperative decrease of serum albumin predicts short-term complications in patients undergoing gastric cancer resection.

World J Gastroenterol

Zhi-Jian Liu, Shi-Chao Ai, Feng Sun, Li Chen, Wen-Xian Guan, Department of Gastrointestinal Surgery, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, Jiangsu Province, China.

Published: July 2017

Aim: To find an accurate and simple predictor for postoperative short-term complications after gastrectomy.

Methods: Two hundred and twenty-three patients undergoing gastric cancer resection between October 1, 2015 and September 30, 2016 were enrolled in this study. Univariate and multivariate analyses were used to identify risk factors for complications after gastrectomy. The cutoff values and diagnostic accuracy were examined by receiver operating characteristic curves.

Results: Sixty-two (27.8%) patients had short-term complications after gastric cancer resection. The postoperative decrease in serum albumin (∆ALB) was an independent risk factor for complications (OR = 17.957, 95%CI: 6.073-53.095, < 0.001). The cutoff value was 14.0% and the area under the curve was higher than that of C-reactive protein on postoperative day 3 (area under the curve: 0.806 0.709). Patients with ∆ALB ≥ 14.0% were more likely to have short-term complications after gastrectomy (46.7% 5.0%, < 0.001), prolonged hospital stay (17.2 ± 10.8 d 14.1 ± 4.2 d, = 0.007) and higher comprehensive complication index ( < 0.001) than those with ∆ALB < 14.0%.

Conclusion: Postoperative ∆ALB with a cutoff of 14.0% can be used to recognize patients who have high risk of short-term complications following gastric cancer resection.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526768PMC
http://dx.doi.org/10.3748/wjg.v23.i27.4978DOI Listing

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