AI Article Synopsis

  • Ductal adenocarcinoma is the most common type of pancreatic cancer, and high-quality imaging helps determine if a patient can undergo potentially curative surgery or if their disease is too advanced.
  • Systemic therapy plays a role in both pre-surgery and post-surgery stages, as well as in managing more severe cases of the cancer.
  • Clinical trials are essential for advancing treatments, and the NCCN Guidelines provide comprehensive strategies for diagnosing and treating pancreatic adenocarcinoma, including surgery, systemic therapy, and radiation.

Article Abstract

Ductal adenocarcinoma and its variants account for most pancreatic malignancies. High-quality multiphase imaging can help to preoperatively distinguish between patients eligible for resection with curative intent and those with unresectable disease. Systemic therapy is used in the neoadjuvant or adjuvant pancreatic cancer setting, as well as in the management of locally advanced unresectable and metastatic disease. Clinical trials are critical for making progress in treatment of pancreatic cancer. The NCCN Guidelines for Pancreatic Adenocarcinoma focus on diagnosis and treatment with systemic therapy, radiation therapy, and surgical resection.

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http://dx.doi.org/10.6004/jnccn.2017.0131DOI Listing

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