Hypersomnia presents as excessive daytime sleepiness with a prevalence of 7.1% in general population. Hypersomnia has serious negative effects on persons functioning. The aetiology of hypersomnia can be due to neurological conditions, primary sleep disorders, Substance induced, Psychiatric disorders and idiopathic. Klein-Levin syndrome (KLS) is condition characterised by hypersomnia, hyperphagia and hypersexuality. Among the psychiatric disorders, hypersomnia is seen in bipolar depression. In bipolar disorder, hypersomnia can be present during the depressive episode and also inter-episodically. Here is a case report on hypersomnia and diagnostic challenges.
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[Kleine-Levin syndrome].
Zh Nevrol Psikhiatr Im S S Korsakova
August 2024
Mental Health Research Center, Moscow, Russia.
Kleine-Levin syndrome (KLS) is manifested by periodic hypersomnolence with an increased appetite and psychopathological symptoms (psychomotor agitation, hallucinations, hypersexuality). The duration of the attack ranges from several days to several weeks. A forced awakening can provoke severe aggressive behavior.
View Article and Find Full Text PDFPediatric Sleep Medicine Cases.
Curr Sleep Med Rep
March 2022
Division of Pediatric Pulmonology and Sleep Medicine, Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA USA.
Purpose Of The Review: In this review, we will discuss commonly encountered pediatric sleep disorders, their clinical presentations, evaluation, and management.
Recent Findings: Sleep problems are common complaints in the pediatric population with an estimated prevalence of at least 25%. This review examines frequently seen pediatric sleep disorders including insomnia, obstructive sleep apnea, hypersomnolence, circadian rhythm sleep-wake disorders, parasomnias, and movement disorders.
Possible role of COVID-19 in the relapse of Klein-Levin Syndrome.
Respir Med Case Rep
May 2021
Departement Pulmonology and Critical Care, Allegheny Health Network, Pittsburgh, PA, USA.
Klein-Levin Syndrome (KLS) is an extremely rare neurological disorder which can manifest as recurring spells of sleepiness, cognitive disturbances and behavioral changes. We present a novel case of KLS relapse in the setting of Coronavirus disease-19 (COVID-19). A 36-year-old male who had a known history of KLS since adolescence was admitted with sleepiness and behavioral disturbances.
View Article and Find Full Text PDFKlein-Levin syndrome versus bipolar disorder not otherwise specified- diagnostic challenges.
Asian J Psychiatr
August 2017
Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore560029, India. Electronic address:
Hypersomnia presents as excessive daytime sleepiness with a prevalence of 7.1% in general population. Hypersomnia has serious negative effects on persons functioning.
View Article and Find Full Text PDFKleine-Levin Syndrome.
Sleep Med Clin
June 2015
Sleep Disorder Unit, National Reference Center for Narcolepsy, Idiopathic Hypersomnia and Kleine Levin syndrome, Inserm U975, Pitié-Salpêtrière Hospital (APHP), Paris 6 University, Paris, France. Electronic address:
Kleine-Levin syndrome is a rare recurrent encephalopathy primarily affecting teenagers, characterized by relapsing-remitting episodes of hypersomnia along with cognitive, psychiatric and behavioral disturbances. During episodes, patients suddenly present hypersomnia (with sleep lasting 15-21 h/d), cognitive impairment (major apathy, confusion, slowness, amnesia), and a specific feeling of derealization (dreamy state, altered perception). Less frequently, they may also experience hyperphagia (66%), hypersexuality (53%, principally men), depressed mood (53%, principally women), anxiety, hallucinations, and acute brief psychosis (33%).
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