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Clinical Phenotypes of Giant Cell Arteritis: Insights into Complications and Survival Outcomes.
Eur J Rheumatol
September 2024
Department of Rheumatology, Hospital Universitari Bellvitge, Universitat de Barcelona (UB), L'Hospitalet de LLobregat, Barcelona, Spain.
Article Synopsis
- Giant cell arteritis (GCA) is a complex disease with various symptoms and severity levels, and the study aimed to evaluate its different clinical subsets to improve treatment strategies and reduce complications.
- The study categorized GCA into three phenotypes: cranial, extracranial, and occult, analyzing their association with severe complications and survival rates over time.
- Results indicated that cranial GCA had more severe ischemic complications and visual disturbances, while the occult subset showed potential for higher mortality, highlighting the need for targeted treatment approaches based on these clinical patterns.
Occult GCA: A rare variant of Giant Cell Arteritis.
Acta Ophthalmol
December 2024
Department of Clinical Sciences and Ophthalmology, Umeå University, Umeå, Sweden.
Updates in non-neoplastic orthopaedic pathology: what you don't know can hurt you!
J Clin Pathol
September 2024
Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio, USA
Article Synopsis
- Most research in surgical pathology tends to focus on rare tumors, while average pathologists deal with common non-neoplastic orthopedic conditions daily, indicating a gap in knowledge for these frequent cases.* -
- Intraoperative consultations, especially for revision arthroplasty infections, are vital, as pathologists help determine the need for antibiotic spacers based on their assessments.* -
- Recent literature highlights the importance of thorough examination of orthopedic specimens, as it can lead to significant insights into conditions like avascular necrosis and even early diagnosis of diseases like cardiac amyloidosis.*
Prevalence and outcome of occult giant cell arteritis.
Eur J Intern Med
August 2024
Department of General Internal Medicine, UZ Leuven, Leuven, Belgium; Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium; European Reference Network for Immunodeficiency, Autoinflammatory, Autoimmune and Pediatric Rheumatic disease (ERN-RITA), Utrecht, The Netherlands.
[Erdheim-Chester disease initially discovered at extraskeletal locations: a clinicopathological analysis of four cases].
Zhonghua Bing Li Xue Za Zhi
April 2024
Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
To investigate the clinicopathological features of Erdheim-Chester disease (ECD) initially diagnosed at extraskeletal locations. Clinical and pathological data of four cases of ECD diagnosed initially in extraskeletal locations were collected at Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, from January 2013 to June 2023. BRAF V600E gene was detected by reverse transcription polymerase chain reaction (RT-PCR).
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