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Liver parasites: A global endemic and journey from infestation to intervention.
World J Gastroenterol
January 2025
Department of Medicine, Section of Gastroenterology, Aga Khan University Hospital, Karachi 75500, Sindh, Pakistan.
Parasites have coexisted with humans throughout history, forming either symbiotic relationships or causing significant morbidity and mortality. The liver is particularly vulnerable to parasitic infections, which can reside in, pass through, or be transported to the liver, leading to severe damage. This editorial explores various parasites that infect the liver, their clinical implications, and diagnostic considerations, as discussed in the article "Parasites of the liver: A global problem?".
View Article and Find Full Text PDFSpecies Identification and Genotyping of Cutaneous Leishmaniasis in Clinical Samples Based on ITS1-PCR-Sequencing in Southeast Iran.
Iran J Public Health
November 2024
Department of Parasitology, School of Medical Sciences, Medical University of Zabol, Zabol, Iran.
Article Synopsis
- Cutaneous leishmaniasis (CL) is prevalent in impoverished areas of Iran, prompting a study to identify its species using molecular and traditional diagnostic techniques.
- A cross-sectional study involving 32 patients in Sistan and Baluchistan Province revealed that PCR testing was the most sensitive method for detecting CL, outperforming culture and microscopy.
- The study identified the predominant species causing CL and underscored the need for molecular methods in species identification to improve understanding of the disease's epidemiology in the region.
Prokaryotic and eukaryotic skin microbiota modifications triggered by Leishmania infection in localized Cutaneous Leishmaniasis.
PLoS Negl Trop Dis
March 2024
Centro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), Facultad de Ciencias Naturales, Universidad del Rosario, Bogotá, Colombia.
Cutaneous Leishmaniasis (CL) is a tropical disease characterized by cutaneous ulcers, sometimes with satellite lesions and nodular lymphangitis. Leishmania parasites, transmitted by sandfly vectors, cause this widespread public health challenge affecting millions worldwide. CL's complexity stems from diverse Leishmania species and intricate host interactions.
View Article and Find Full Text PDFSix-Year Study on Cutaneous Leishmaniasis in Al-Muthanna, Iraq: Molecular Identification Using ITS1 Gene Sequencing.
Infect Chemother
June 2024
Department of Nursing Techniques, Al-Nasiriyah Technical Institute, Southern Technical University, Thi-Qar, Iraq.
Article Synopsis
- - The study investigated the prevalence of cutaneous leishmaniasis (CL) in Al-Muthanna province, Iraq, from 2015 to 2020, focusing on the identification of species responsible for infections among patients during the first half of 2020.
- - A total of 2,325 patients were analyzed, with the highest infection rates found in children aged 5-14 years, and infections peaked during the winter months, especially in January.
- - The results revealed that two species of parasites were identified in the samples, highlighting the need for molecular diagnosis to improve treatment and control strategies for CL in the region.
Overlapping between squamous cell carcinoma and mucocutaneous leishmaniasis in a diabetic patient.
Oxf Med Case Reports
February 2024
Department of Dermatology, Duraykish National Hospital, Tartous, Syria.
Mucocutaneous leishmaniasis (MCL) is a leishmania infection; that usually affects the oral and nasal mucosa. The coexistence of leishmania and malignancy is rarely reported and mainly in immunocompromised patients. We report a case of an overlapping between leishmania and squamous cell carcinoma (SCC) in a 60-year-old immunocompetent Syrian female.
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