Objectives: Dental amalgam has been used as a common restorative material since the 1800s, but concerns have been raised regarding its purported neuropsychological effects due to the neurotoxicity of mercury. In this study, a nationwide population-based database was employed to investigate the association of dental amalgam restoration with the risk of attention-deficit/hyperactivity disorder (ADHD).
Methods: After matching, 88 068 young people with at least one tooth restoration during 2002-2010 and no ADHD history before 2001 were selected and then collected the further information until the end of 2011. Cox proportional hazard models were employed to estimate the possible effect of amalgam restorations on the risk of ADHD during the period of 2002-2011. Subgroup analyses were performed according to age, sex and number of amalgam restorations.
Results: In total, 2073 people (2.4%) received an ADHD diagnosis during the study period, yielding an incidence rate of 32.4 per 100 000 person-years. Those who had 6 or more amalgam restorations had a higher risk of future ADHD in the unadjusted Cox proportional hazard regression model (hazard ratio=1.20, 95% confidence interval [CI]=1.04-1.38, P=.015) than those who had received composite resin or glass ionomer restorations. However, after adjustment for potential confounding factors, the result was found to be confounded by age.
Conclusions: The univariate analysis results showed that those who had 6 or more amalgam restorations had a 20% higher risk of future ADHD; however, the association disappeared after the model was adjusted for age. Despite this study analysing a larger sample than those analysed in previous studies, no association was observed between young patients' having received amalgam restorations and a future ADHD diagnosis. Further research aimed at evaluating the association between dental amalgam and other subsequent neuropsychological effects is warranted, especially for people who are vulnerable to mercury exposure.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/cdoe.12327 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Objectives: To compare trends in teaching and placement of composite resin versus amalgam in posterior restorations in Canadian dental schools with those in the United States.
Methods: Secondary descriptive and statistical analyses were performed on data from 2 previous studies. The data consisted of responses to questionnaires on teaching policies and the proportion of posterior restorations (amalgam and composite resin) performed in Canadian and US dental schools.
Teaching posterior composite restorations: A survey of dental schools in Palestine.
Heliyon
October 2024
Faculty of Dentistry, Arab American University, Palestine.
Aim: This study aimed to assess different aspects of teaching posterior composite restorations in two dental schools in Palestine.
Materials And Methods: A questionnaire was emailed to the heads of the operative and conservative dentistry departments to collect detailed information on the teaching practices related to posterior composite restorations. The questionnaire comprised 22 questions structured to collect information on the time dedicated to teaching the topic, competency assessments, future plans for allocating time for each restoration type, relevant indications and contraindications, specific materials and techniques utilized in the application, and fees charged for posterior restorations.
Systematic review: oral and maxillofacial radiology as fundamental methods of virtual autopsy.
Forensic Sci Res
September 2023
Department of Oral and Maxillofacial Radiology-Forensic Odontology, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia.
Article Synopsis
- Refusal of autopsy can happen for reasons like religious beliefs and concerns about diseases, prompting interest in alternative methods like virtual forensic odontological autopsy.
- The study systematically reviewed literature from December 2021 to October 2022 to assess the use of oral and maxillofacial radiology as a non-invasive technique for virtual autopsy.
- Four main imaging techniques were identified for virtual autopsy in forensic odontology, including CT scanning (multidetector CT), cone beam CT, and magnetic resonance imaging, each with unique benefits.
Effects of Finishing on Surface Roughness of Four Different Glass-Ionomer Cements and One Alkasite: In Vitro Investigation over Time Using Aging Simulation.
J Funct Biomater
October 2024
Division of Restorative Dentistry, Periodontology and Prosthodontics, Dental Medicine and Oral Health, Medical University of Graz, 8010 Graz, Austria.
Article Synopsis
- In 2017, Europe banned the use of amalgam fillings for children under 15 and pregnant/breastfeeding women, creating a demand for better alternative materials.
- This study tested the surface roughness of five different amalgam-replacement materials using six finishing techniques across three time points, involving 960 samples made from 3D-printed molds.
- Results showed that conventional and hybrid glass-ionomer cements had smoother surfaces than high-viscosity alternatives, with some materials demonstrating stable roughness over time, emphasizing the need for careful selection of finishing methods.
Evaluating the effect of amalgam fillings on caries detection in cone-beam computed tomography images.
Dent Res J (Isfahan)
September 2024
Department of Maxillofacial Surgery, Dental Implants Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Dental caries stands as one of the most prevalent dental concerns, with early diagnosis being pivotal in clinical dentistry. Cone-beam computed tomography (CBCT) emerges as a widely utilized modality for dental caries identification, owing to its significant advantages. However, there remains a considerable knowledge gap regarding the efficacy of CBCT scans in detecting dental caries.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!