This manuscript describes the case of a patient with sickle cell anemia who died of fulminant hepatitis after therapy with the iron chelator Deferasirox. The patient was homozygous for the -1774delG polymorphism in the gene, which raises the concern about the use of hepatotoxic drugs in this specific context.
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| http://dx.doi.org/10.1002/ccr3.1040 | DOI Listing |
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