Generalized joint hypermobility (GJH) is a risk factor for developing adolescent idiopathic scoliosis (AIS); however, it is not known whether joint hypermobility influences the risk of progression to surgery. Beighton joint hypermobility scores were assessed in 570 female AIS patients. Multivariate analysis was carried out to determine whether Beighton hypermobility scores were predictors of surgical intervention. In this female AIS cohort, 24.7% (141/570) had GJH (Beighton score ≥4). Multivariate analysis showed that GJH did not influence the risk of surgery, although having no joint hypermobility (Beighton score=0) increased risk (odds ratio: 1.89; P=0.003). Females who had no hypermobility (score=0) had significantly larger curves than individuals who scored at least one point on the Beighton scale [50° (interquartile range: 26) vs. 42° (interquartile range: 24), P=0.001]. Evaluation of specific measures of joint hypermobility indicated that females who could not touch their palms to the floor were 2.1-fold more likely to have surgery than patients who could perform this task (P=0.001). None of the other features measured on the Beighton score correlated with surgical risk. The lack of joint hypermobility increases the odds of surgery in females with AIS. Specifically, inability to touch the palms to the floor is an indicator of progression to surgery.
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http://dx.doi.org/10.1097/BPB.0000000000000489 | DOI Listing |
PLoS One
January 2025
Shi's Traumatology Medical Center of Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Pu Dong New District, Shanghai, China.
Background: Ankle sprain is a common clinical disease, which has the highest incidence rate among joint and ligament injuries. And acute ankle sprains can easily develop into chronic ankle instability, thereby increasing the difficulty of treatment. The current clinical guidelines for post-acute ankle sprains are still controversial.
View Article and Find Full Text PDFRev Med Suisse
January 2025
Centre pédiatrique de Meyrin, Rue de la Prulay 35, 1217 Meyrin.
Joint hypermobility is a common feature in children and adolescents, often physiological and benign, but it is also a manifestation of hereditary connective tissue disorders. In pediatrics, there is a real need to differentiate Ehlers-Danlos syndrome (EDS) hypermobile type (hEDS) from benign hypermobility, in the absence of a genetic marker specific to this form of EDS. In 2023, the International Ehlers-Danlos Consortium revised the diagnostic criteria for children and adolescents, introducing the concept of hypermobility spectrum disorder.
View Article and Find Full Text PDFSci Robot
January 2025
Biorobotics Laboratory, Soft Robotics Research Center, Institute of Advanced Machines and Design, Department of Mechanical Engineering, Institute of Engineering, Seoul National University, Seoul, Republic of Korea.
Snap-through, a rapid transition of a system from an equilibrium state to a nonadjacent equilibrium state, is a valuable design element of soft devices for converting a monolithic stimulus into systematic responses with impulsive motions. A common way to benefit from snap-through is to embody it within structures and materials, such as bistable structures. Torque-reversal mechanisms discovered in nature, which harness snap-through instability via muscular forces, may have comparative advantages.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
University of Maryland, College Park, Joint Quantum Institute, Condensed Matter Theory Center and, Department of Physics, Maryland 20742-4111, USA.
Discrete time crystals are novel phases of matter that break the discrete time translational symmetry of a periodically driven system. In this Letter, we propose a classical system of weakly nonlinear parametrically driven coupled oscillators as a test bed to understand these phases. Such a system of parametric oscillators can be used to model period-doubling instabilities of Josephson junction arrays as well as semiconductor lasers.
View Article and Find Full Text PDFSpine (Phila Pa 1976)
January 2025
Department of Neurosurgery, Lilavati Hospital and Research Center, Bandra, Mumbai, India.
Study Design: A systematic literature review and consensus using Delphi method.
Objective: The aim was to formulate consensus recommendations regarding the natural history, diagnosis, classification and optimal treatment of Os Odontoideum with global applicability.
Summary Of Background: Os odontoideum (OO) is a rare anomaly of the cranio-vertebral junction (CVJ).
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