Amphiphilic Peptide Self-Assembly: Expansion to Hybrid Materials.

Biomacromolecules

University of Basel, Department of Chemistry, Klingelbergstrasse 80, 4056 Basel, Switzerland.

Published: November 2017

The design of functional systems with sizes in the nanometer range is a key challenge in fields such as biomedicine, nanotechnology, and engineering. Some of the most promising materials nowadays consist of self-assembling peptides or peptide-polymer hybrid materials because of their versatility and the resulting properties that can be achieved with these structures. Self-assembly of pure amphiphilic peptides or in combination with block copolymers results in a large variety of nanostructures (micelles, nanoparticles (NPs), compartments, planar membranes) each with different characteristics and tunable properties. Here, we describe such novel peptide- or peptide-polymer-based supramolecular nanostructures and emphasize their functionality and various promising applications.

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http://dx.doi.org/10.1021/acs.biomac.7b00764DOI Listing

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