AI Article Synopsis
- A study of 302 falciparum malaria cases, including 30 severe cases, highlighted common symptoms like intermittent fever, chills, and headaches, with cough and pyuria also prevalent.
- A total of 16.6% of patients had anemia, and hypoglycemia was not observed in any cases.
- Treatment with quinine, tetracycline, and sulfadoxine-pyrimethamine resulted in a 100% cure rate for uncomplicated chloroquine-resistant malaria, while amodiaquine with tetracycline and sulfadoxine-pyrimethamine was effective in 76.2% of uncomplicated cases.
Article Abstract
Three hundred and two cases of falciparum malaria including 30 cases of severe falciparum malaria admitted between Jan 93 - Dec 93 were studied for their clinical features and response to treatment. Intermittent or remittent fever with chills and headache were the commonest presentation noted (99.3%). Cough (46.4%), hyperbilirubinemia (31.8%), and pyuria (52.9%) were the other notable features. Anaemia was uncommon (16.6%). Hypoglycacmia was detected in none of the cases. Quinine for 3 days along with tetracycline and sulfadoxine - pyrimethamine achieved a 100 per cent cure rate in uncomplicated chloroquine resistant falciparum malaria. Amodiaquine along with tetracycline and sulfadoxine - pyrimethamine was effective in 76.2 per cent of uncomplicated cases.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531211 | PMC |
| http://dx.doi.org/10.1016/S0377-1237(17)30396-9 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Low levels of Plasmodium falciparum parasitaemia among patients receiving antiretroviral therapy at the treatment centre of the Regional Hospital Bamenda, Northwest Cameroon.
PLoS One
January 2025
Department of Biomedical Sciences, Faculty of Health Sciences, University of Bamenda, Bambili, North West Region, Cameroon.
Background: Malaria and HIV are leading causes of death in Africa, including Cameroon. Antiretroviral therapy (ART) is expected to boost immunity and reduce vulnerability to opportunistic infections. Reports on comorbidities including malaria are common in Cameroon.
View Article and Find Full Text PDFVirus-like particle-based vaccines targeting the mosquito salivary protein TRIO.
mSphere
January 2025
Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
Malaria is a highly lethal infectious disease caused by parasites. These parasites are transmitted to vertebrate hosts when mosquitoes of the genus probe for a blood meal. Sporozoites, the infectious stage of , transit to the liver within hours of injection into the dermis.
View Article and Find Full Text PDF[Investigation of Molecular Differences in Plasmodium spp. Isolates Obtained from Malaria Patients].
Mikrobiyol Bul
January 2025
Sağlık Bilimleri Üniversitesi, Kayseri Şehir Eğitim ve Araştırma Hastanesi, Parazitoloji Laboratuvarı, Kayseri.
Sıtma, her yıl dünya nüfusunun yarısından fazlası için ciddi bir tehdit oluşturmaya devam etmektedir. Hastalığa neden olan Plasmodium parazitleri, yalnızca insanlarla sınırlı kalmayıp sürüngenlerden kuşlara, memelilerden diğer omurgalılara dek geniş enfeksiyon yelpazesine sahiptir. Plasmodium türleri, çevredeki değişikliklere uyum sağlamalarını sağlayan olağanüstü genetik esnekliğe sahiptir ve bu da onlara sıtma ilaçları gibi tedavi edici maddelere karşı hızla direnç geliştirme ve konakçı özgüllüğünü değiştirme potansiyeli verir.
View Article and Find Full Text PDF: Assessing vector bionomics is crucial to improving vector control strategies. Several entomological studies have been conducted to describe malaria transmission in different eco-epidemiological settings in Cameroon; knowledge gaps persist, particularly in highland areas. This study aimed to characterize malaria vectors in three localities along an altitudinal gradient in the western region: Santchou (700 m), Dschang (1400 m), and Penka Michel (1500 m).
View Article and Find Full Text PDFCerebral malaria (CM) is a severe complication of Plasmodium falciparum infection, with resistance to antimalarial drugs, including artemisinin-based combination therapies(ACTs), posing a significant threat. CD4+ naive cells expressing CCR7 are known to play a protective role, as they readily migrate to secondary lymphoid tissues activated by CCL19 chemokines. In an effort to address this challenge, we investigated the impact of Annona muricata, an herbaceous and immunomodulatory plant, on CCL19 concentration.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!