In recent years, several automated analysers that prepare and stain blood smears have been introduced in clinical laboratories. Despite the use of instrumental settings based on physical characteristic of individual samples, traumatic injuries of neutrophil and lymphocytes can be observed. Some samples present a very high percentage of damaged cells, allowing the speculation that a cellular susceptibility may enhance mechanical traumatism. These artefacts can puzzle morphological evaluation in both traditional and digitised microscopy; in addition, unskilled operators can be misled.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1136/jclinpath-2017-204580 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The fixed-effects model for robust analysis of stepped-wedge cluster trials with a small number of clusters and continuous outcomes: a simulation study.
Trials
October 2024
Centre for Quantitative Medicine, Duke-NUS Medical School, 8 College Road, Singapore, 169857, Singapore.
Background: Stepped-wedge cluster trials (SW-CTs) describe a cluster trial design where treatment rollout is staggered over the course of the trial. Clusters are commonly randomized to receive treatment beginning at different time points in this study design (commonly referred to as a Stepped-wedge cluster randomized trial; SW-CRT), but they can also be non-randomized. Trials with this design regularly have a low number of clusters and can be vulnerable to covariate imbalance.
View Article and Find Full Text PDFCone-beam CT volumetry: a new method for evaluating osteotomy healing - a clinical evaluation and MDCT comparison.
Acta Radiol
November 2024
Department of Radiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Article Synopsis
- Fracture healing issues are significant in trauma care, and an open wedge osteotomy of the distal radius offers a way to assess healing, particularly using cone-beam computed tomography (CBCT), which is preferred for analyzing hand and wrist bones.
- This study evaluated the healing of osteotomies in 36 patients using both CBCT and multidetector CT (MDCT), comparing two methods of volumetric measurement and checking the reliability of these techniques.
- Results showed that CBCT volumetry is a reliable and effective method for measuring osteotomy healing, with high consistency compared to MDCT and strong reliability in segmentation and observer assessments.
Accurate size-based protein localization from cryo-ET tomograms.
J Struct Biol X
December 2024
Department of Computer Science, Duke University, Durham, USA.
Cryo-electron tomography (cryo-ET) combined with sub-tomogram averaging (STA) allows the determination of protein structures imaged within the native context of the cell at near-atomic resolution. Particle picking is an essential step in the cryo-ET/STA image analysis pipeline that consists in locating the position of proteins within crowded cellular tomograms so that they can be aligned and averaged in 3D to improve resolution. While extensive work in 2D particle picking has been done in the context of single-particle cryo-EM, comparatively fewer strategies have been proposed to pick particles from 3D tomograms, in part due to the challenges associated with working with noisy 3D volumes affected by the missing wedge.
View Article and Find Full Text PDF3D U-Net Neural Network Architecture-Assisted LDCT to Acquire Vertebral Morphology Parameters: A Vertebral Morphology Comprehensive Analysis in a Chinese Population.
Calcif Tissue Int
October 2024
Medical 3D Printing Center, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou, 450052, China.
To evaluate the feasibility of acquiring vertebral height from chest low-dose computed tomography (LDCT) images using an artificial intelligence (AI) system based on 3D U-Net vertebral segmentation technology and the correlation and features of vertebral morphology with sex and age of the Chinese population. Patients who underwent chest LDCT between September 2020 and April 2023 were enrolled. The Altman and Pearson's correlation analyses were used to compare the correlation and consistency between the AI software and manual measurement of vertebral height.
View Article and Find Full Text PDFThe Integration of ANN and FEA and Its Application to Property Prediction of Dual-Performance Turbine Disks.
Materials (Basel)
June 2024
State Key Laboratory of Powder Metallurgy, Central South University, Changsha 410083, China.
Regulating the microstructure of powder metallurgy (P/M) nickel-based superalloys to achieve superior mechanical properties through heat treatment is a prevalent method in turbine disk design. However, in the case of dual-performance turbine disks, the complexity and non-uniformity of the heat treatment process present substantial challenges. The prediction of yield strength is typically derived from the analysis of microstructures under various heat treatment regimes.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!