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Case report: Placental chorioadenoma in a primiparous pug dog.
Front Vet Sci
November 2024
Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Blacksburg, VA, United States.
A single 1.7 cm × 1.2 cm × 1 cm focal, raised, smooth, round, pink to flesh-colored mass protruding from the chorioallantois of the zonary placenta was found during Cesarean section in a primiparous pug bitch.
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- Genistin, an isoflavone found in soybeans, was tested on 72 gestating sows to see how it affects reproductive performance and immunity by supplementing their diet with 150 mg/kg.
- Results indicated that genistin significantly improved the number of live piglets and reduced stillbirth rates, although it also led to lighter average weights for the live-born piglets.
- The experiment also showed that genistin increased key immune markers in the sows while potentially reducing certain cholesterol levels later in gestation, indicating it has various beneficial effects on both the sows and their litters.
Capture of Totipotency in Mouse Embryonic Stem Cells in the Absence of Pdzk1.
Adv Sci (Weinh)
December 2024
State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai Animal Resources Center and Reproductive Regulation, Institute of Transplantation Medicine, Nankai University, Tianjin, 300350, China.
Totipotent cells can differentiate into three lineages: the epiblast, primitive endoderm, and trophectoderm. Naturally, only early fertilized embryos possess totipotency, and they lose this ability as they develop. The expansion of stem cell differentiation potential has been a hot topic in developmental biology for years, particularly with respect to the generation totipotent-like stem cells.
View Article and Find Full Text PDFMaternal supplementation spermidine during gestation improves placental angiogenesis and reproductive performance of high prolific sows.
J Nutr Biochem
February 2025
College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China; Frontiers Science Center for Animal Breeding and Sustainable Production, Wuhan, China. Electronic address:
Article Synopsis
- Spermidine (SPD) is a polyamine that may improve placental vascular development in pregnant sows, potentially leading to heavier piglets.
- In a study with 609 sows, those receiving 10 mg/kg of SPD showed increased healthy piglet count and placental efficiency, while the 20 mg/kg group further improved certain placental functions and reduced mummified fetus numbers.
- Overall, supplementing sows with SPD during pregnancy appears to enhance litter health and placental development, indicating it could benefit sow production performance.
Analysis of the evolution of placental oxidative stress research from a bibliometric perspective.
Front Pharmacol
October 2024
Department of Obstetrics and Gynecology, Women's Hospital of Jiangnan University, Wuxi Maternity and Child Health Care Hospital, Wuxi, China.
Background: Research on placental oxidative stress is pivotal for comprehending pregnancy-related physiological changes and disease mechanisms. Despite recent advancements, a comprehensive review of current status, hotspots, and trends remains challenging. This bibliometric study systematically analyzes the evolution of placental oxidative stress research, offering a reference for future studies.
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