In this work, Al-B₄C nanocomposites were produced by microwave sintering and followed by hot extrusion processes. The influence of ceramic reinforcement (B₄C) nanoparticles on the physical, microstructural, mechanical, and thermal characteristics of the extruded Al-B₄C nanocomposites was investigated. It was observed that the density decreased and porosity increased with an increase in B₄C content in aluminum matrix. The porosity of the composites increased whereas density decreased with increasing B₄C content. Electron microscopy analysis reveals the uniform distribution of B4C nanoparticles in the Al matrix. Mechanical characterization results revealed that hardness, elastic modulus, compression, and tensile strengths increased whereas ductility decreases with increasing B₄C content. Al-1.0 vol. % B₄C nanocomposite exhibited best hardness (135.56 Hv), Young's modulus (88.63 GPa), and compression/tensile strength (524.67/194.41 MPa) among the materials investigated. Further, coefficient of thermal expansion (CTE) of composites gradually decreased with an increase in B₄C content.
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http://dx.doi.org/10.3390/ma10060621 | DOI Listing |
The kinetically-derived maximal dose (KMD) is defined as the maximum external dose at which kinetics are unchanged relative to lower doses, e.g., doses at which kinetic processes are not saturated.
View Article and Find Full Text PDFCell Mol Biol (Noisy-le-grand)
January 2025
Department of Chemistry, Rabigh College of Sciences and Arts, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
A medicinal plant is any plant that in one or more of its organs contains substances that can be used by it or their constituent for therapeutic purposes. The present work was done to evaluate pharmacognostic, fluorescence, proximate and phytochemical analysis of ethanolic extracts of Cistanche tubulosa (Orobanchaceae) along with antimicrobial activity. Antimicrobial activity against four bacterial strains S.
View Article and Find Full Text PDFPak J Pharm Sci
January 2025
College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, China/Province Multi-Component Chinese Medicine Engineering Technology Research Center of Liaoning, Dalian, China/Modern Traditional Chinese Medicine Research and Engineering Laboratory of Liaoning, Dalian, China.
Chebulagic acid and chebulinic acid are the two tannin compounds with the highest content in Terminalia chebula, they were separated by ODS column eluted with 20% methanol and 35% methanol, respectively. The compounds were identified by comparing the data of H NMR and C NMR with the literature; HPLC method was used to investigate the stable storage conditions of chebulagic acid and chebulinic acid; lipopolysaccharide (LPS) induced in vivo inflammation model and RAW264.7 macrophage in vitro inflammatory model to evaluate the anti-inflammatory activities of chebulagic acid and chebulinic acid.
View Article and Find Full Text PDFJ Public Health (Oxf)
January 2025
Lifespan and Population Health, School of Medicine, University of Nottingham, Nottingham NG5 1PB, UK.
Background: Alcohol misuse is linked to numerous health and socioeconomic harms. Edutainment and docutainment television programmes can act as health promotion tools, influencing health perceptions and behaviours. Inaccurate portrayals can engender misinformation.
View Article and Find Full Text PDFXi Bao Yu Fen Zi Mian Yi Xue Za Zhi
January 2025
Department of Neurosurgery, Wuhan NO.1 Hospital, Wuhan 432000, China. *Corresponding author, E-mail:
Objective To investigate the effects and molecular mechanism of Homer protein homolog 1a (Homer 1a) overexpression on nerve injury in mice with traumatic brain injury (TBI). Methods Sixty male C57BL/6 mice were randomly divided into five groups: sham group, TBI group, empty lentivirus (Lv-NC) group, Homer 1a overexpression lentivirus (Lv-Homer 1a) group and Lv-Homer 1a + 740 Y-P group, with 12 mice in each group. The lentivirus was orthotopic injected into the cerebral cortex of mice 5 d before modeling, while 740 Y-P was injected intraperitoneally 1 d before modeling.
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