Complex liver cysts in Autosomal Dominant Polycystic Kidney Disease.

Purpose: To determine prevalence of complex liver cysts in Autosomal Dominant Polycystic Kidney Disease (ADPKD).

Methods: Abdominal MRI in 186 ADPKD subjects were evaluated by two independent observers to determine prevalence of complex liver cysts.

Results: 23 (12%) of subjects, had at least 1 complex cyst. Only 8 (4%) were reported to have a complex cyst prospectively, representing an under-reporting rate of 65%. Median total cyst volume was 66-times greater for subjects with complex cysts compared to subjects without (p<0.0001).

Conclusion: Complex hepatic cysts were observed in 12% of ADPKD cases, occurring more frequently in livers with extensive cystic involvement.