AI Article Synopsis

  • The study aimed to determine if a spontaneous breathing test could predict extubation failure in pediatric patients who had been mechanically ventilated.
  • A total of 95 children were analyzed, with 71 in the Test Group (who underwent the breathing test before extubation) and 24 in the Control Group (who were extubated without the test), revealing no significant differences in their respiratory parameters.
  • The findings indicated that the Control Group had a 1.412 times higher likelihood of extubation failure compared to the Test Group, but this was not statistically significant, leading to the conclusion that the spontaneous breathing test does not effectively predict extubation failure in children.

Article Abstract

Objective: To assess whether the spontaneous breathing test can predict the extubation failure in pediatric population.

Methods: A prospective and observational study that evaluated data of inpatients at the Pediatric Intensive Care Unit between May 2011 and August 2013, receiving mechanical ventilation for at least 24 hours followed by extubation. The patients were classified in two groups: Test Group, with patients extubated after spontaneous breathing test, and Control Group, with patients extubated without spontaneous breathing test.

Results: A total of 95 children were enrolled in the study, 71 in the Test Group and 24 in the Control Group. A direct comparison was made between the two groups regarding sex, age, mechanical ventilation time, indication to start mechanical ventilation and respiratory parameters before extubation in the Control Group, and before the spontaneous breathing test in the Test Group. There was no difference between the parameters evaluated. According to the analysis of probability of extubation failure between the two groups, the likelihood of extubation failure in the Control Group was 1,412 higher than in the Test Group, nevertheless, this range did not reach significance (p=0.706). This model was considered well-adjusted according to the Hosmer-Lemeshow test (p=0.758).

Conclusion: The spontaneous breathing test was not able to predict the extubation failure in pediatric population.

Objetivo: Avaliar se o teste de respiração espontânea pode ser utilizado para predizer falha da extubação na população pediátrica.

MÉtodos: Estudo prospectivo, observacional, no qual foram avaliados todos os pacientes internados no Centro de Terapia Intensiva Pediátrica, no período de maio de 2011 a agosto de 2013, que utilizaram ventilação mecânica por mais de 24 horas e que foram extubados. Os pacientes foram classificados em dois grupos: Grupo Teste, que incluiu os pacientes extubados depois do teste de respiração espontânea; e Grupo Controle, pacientes foram sem teste de respiração espontânea.

Resultados: Dos 95 pacientes incluídos no estudo, 71 crianças eram do Grupo Teste e 24 eram do Grupo Controle. Os grupos foram comparados em relação a: sexo, idade, tempo de ventilação mecânica, indicação para início da ventilação mecânica e parâmetros ventilatórios pré-extubação, no Grupo Controle, e pré-realização do teste, no Grupo Teste. Não foram observadas diferenças entre os parâmetros analisados. Em relação à análise da probabilidade de falha da extubação entre os dois grupos de estudo, a chance de falha do Grupo Controle foi 1.412 maior do que a das crianças do Grupo Teste, porém este acréscimo não foi significativo (p=0,706). O modelo foi considerado bem ajustado de acordo com o teste de Hosmer-Lemeshow (p=0,758).

ConclusÃo: O teste de respiração espontânea para a população pediátrica não foi capaz de prever a falha da extubação.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609611PMC
http://dx.doi.org/10.1590/S1679-45082017AO3913DOI Listing

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