The Use of Ultrabrief Left Unilateral Electroconvulsive Therapy in a Patient With Cerebral Aneurysms and Right-Sided Encephalomalacia and Stroke: A Case Report.

J ECT

Interventional Psychiatry Division, Beacon Health System-Behavior Health, Indiana University School of Medicine-South Bend Campus, 707 N Michigan St, South Bend, IN 46601 Interventional Psychiatry Division, Beacon Health System-Behavior Health, South Bend, IN; and Department of Psychiatry, Mansoura University College of Medicine, Mansoura City, Egypt Interventional Psychiatry Division, Beacon Health System-Behavior Health. Indiana University School of Medicine, South Bend, IN.

Published: December 2017

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http://dx.doi.org/10.1097/YCT.0000000000000442DOI Listing

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We describe a case of a right-handed, 42-year-old, Caucasian female patient who manifested a set of unusual adverse effects during maintenance ultrabrief right-unilateral electroconvulsive therapy (ECT)-generalized myoclonic secondary seizure with lateralization nonresponsive to repeated intravenous diazepam application, deviation of the tongue and the head to the left, ping-pong gaze with nystagmoid jerks, postictal hypoactive confusion state lasting 15 minutes (with a total time to recovery 30 minutes), and likely Todd's paralysis after the procedure (subsided within 24 hours). These adverse effects led to a thorough clinical investigation and eventually the discovery of a brain tumor. In the article, we hypothesize about the possible interaction between the intracranial mass and ECT and provide a literature overview on the topic.

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The Use of Ultrabrief Left Unilateral Electroconvulsive Therapy in a Patient With Cerebral Aneurysms and Right-Sided Encephalomalacia and Stroke: A Case Report.

J ECT

December 2017

Interventional Psychiatry Division, Beacon Health System-Behavior Health, Indiana University School of Medicine-South Bend Campus, 707 N Michigan St, South Bend, IN 46601 Interventional Psychiatry Division, Beacon Health System-Behavior Health, South Bend, IN; and Department of Psychiatry, Mansoura University College of Medicine, Mansoura City, Egypt Interventional Psychiatry Division, Beacon Health System-Behavior Health. Indiana University School of Medicine, South Bend, IN.

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Objective: Characterization of the ictal electroencephalogram (EEG) generated during ultrabrief pulse electroconvulsive therapy (ECT) is important to progress its use in routine ECT practice particularly in indicating treatment efficacy. The study compared 2- to 5-Hz and 5.2- to 13-Hz bands of the ictal EEG signal between brief- and ultrabrief-pulse ECT.

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Background: Metabolic changes after electroconvulsive therapy (ECT) have been described in depressed patients, but results are heterogeneous. To determine the concentrations of N-acetyl-aspartate (NAA), choline-containing compounds, creatine + phosphocreatine (tCr), and glutamate in the left dorsolateral prefrontal cortex (DLPFC) and left anterior cingulum of depressed patients before and after ECT, we used proton magnetic resonance spectroscopy.

Methods: Metabolite concentrations in the DLPFC and anterior cingulum were determined in 25 patients with major depressive disorder (MDD) and 27 healthy control subjects using the point resolved spectroscopy sequence.

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